Green preparation of hydrogel particles-in-emulsions for simultaneous enhancement of humoral and cell-mediated immunity

Green preparation of hydrogel particles-in-emulsions for simultaneous enhancement of humoral and cell-mediated immunity

by Ann Ruiz Posted on

Emulsions are one of essentially the most usually used vaccine adjuvant formulations. Although they promote excessive humoral immunity, the induced mobile immunity is commonly poor, which prohibit their utility. To improve the mobile immunity, some researchers have ready combined formulations by including particles into the aqueous part of emulsions. However, the particle preparation course of normally includes the addition and elimination of natural reagents, which is environmentally unfriendly and cumbersome. Moreover, the obtained vaccine adjuvant solely induces restricted cell-mediated immunity and humoral immunity in contrast with emulsion-adjuvanted vaccines.

Herein, we developed a inexperienced and easy technique for fabricating a novel nanoparticles-in-emulsions (NPE) formulation. Firstly, a temperature-sensitive hydrogel was used to organize particles by self-solidification with out extra crosslinking reagents. Secondly, the white oil was used as natural part to keep away from the particle washing procedures and natural solvent residues. Moreover, the impact of NPE as vaccine adjuvant was evaluated through the use of two veterinary vaccines as mannequin antigens. NPE confirmed benefits than the traditional vaccine formulations in inducing each humoral and mobile immunity. This work gives a facile and broadly relevant method for getting ready nanoparticles-in-emulsions formulation, and presents an efficient adjuvant for enhancing immunity in opposition to infectious ailments.

Effects of zearalenone on genital organ growth, serum immunoglobulin, antioxidant capability, intercourse hormones and liver operate of prepubertal gilts

The research aimed to look at the consequences of zearalenone on genital organ growth, serum immunoglobulin, antioxidant capability, intercourse hormones and liver operate of prepubertal gilts. Forty-eight prepubertal gilts (Landrace × Yorkshire) had been randomly divided into three therapy (T1, T2 and T3) teams and a management group (12 replicates per group, 1 gilt per replicate). Prepubertal gilts within the management group had been fed with basal food regimen, and these in T1, T2 and T3 teams had been fed with basal diets supplemented with 200 μg/kg, 800 μg/kg and 1600 μg/kg zearalenone in the course of the experiment interval, which lasted for 14 d. Feed consumption was counted and vulvar space was measured. The blood samples had been collected from the anterior vena cava of 6 prepubertal gilts in every group, and immunoglobulins, antioxidant indexes, inflammatory cytokines, genital hormones, and biochemical indexes had been analyzed by enzyme-linked immunosorbent assay.

The outcomes confirmed that the common every day feed consumption of prepubertal gilts in every group had no important change (p > 0.05). On 14 d, in contrast with the management group, the vulva space of prepubertal gilts in every therapy group was considerably elevated (p < 0.05). Compared with the management group, the serum immunoglobulin G content material within the T3 group was considerably lowered (p < 0.05). The actions of complete antioxidant capability and the superoxide dismutase of serum within the T3 group had been considerably lowered (p < 0.05). Compared with the management group, the serum interleukin-Four content material in every take a look at group had been extraordinarily considerably elevated (p < 0.01).

The serum contents of luteinizing hormone within the T2 and T3 teams and estradiol within the T3 group had been considerably lowered (p < 0.05) than that of management group. Compared with the management group, the exercise of aspartate aminotransferase in T3 group was considerably elevated (p < 0.05). In conclusion, zearalenone has no considerably impact on the feed consumption of prepubertal gilts, however it may cut back its serum immunoglobulin contents and antioxidant properties, disrupt the secretion of intercourse hormones, enhance the vulva space, produce reproductive toxicity and trigger liver harm. Therefore, in pig manufacturing, the use of antimould reagent along with merchandise of immunity-boosting, antioxidant, anti-inflammatory and hepatoprotective could improve safety.

Green preparation of hydrogel particles-in-emulsions for simultaneous enhancement of humoral and cell-mediated immunity

A Novel In-Cell ELISA Assay Allows Rapid and Automated Quantification of SARS-CoV-2 to Analyze Neutralizing Antibodies and Antiviral Compounds

The coronavirus illness 2019 (COVID-19) brought on by the extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is presently essentially the most urgent medical and socioeconomic problem. Constituting essential correlates of safety, the willpower of virus-neutralizing antibodies (NAbs) is indispensable for convalescent plasma choice, vaccine candidate analysis, and immunity certificates. In distinction to plain serological ELISAs, plaque discount neutralization checks (PRNTs) are laborious, time-consuming, costly, and restricted to specialised laboratories.

To change microscopic counting-based SARS-CoV-2 PRNTs by a novel assay exempt from genetically modified viruses, that are inapplicable in most diagnostics departments, we established a easy, fast, and automated SARS-CoV-2 neutralization assay using an in-cell ELISA (icELISA) method. After optimization of varied parameters similar to virus-specific antibodies, cell strains, virus doses, and length of an infection, SARS-CoV-2-infected cells turned amenable as direct antigen supply for quantitative icELISA.

Recombinant Escherichia coli Microcin H47 (mchB)
CSB-CF351165ENL 11438 mg Ask for price

Recombinant Escherichia coli Microcin J25 (mcjA)
CSB-EP894911ENL 11280 mg Ask for price

Recombinant human Innate immunity activator protein
P1297 100ug Ask for price
Description: Recombinant protein for human Innate immunity activator protein

Recombinant Escherichia coli Colicin-Ia immunity Protein (aa 1-111)
VAng-Lsx02230-inquire inquire Ask for price
Description: Escherichia coli Colicin-Ia immunity protein, recombinant protein.

Recombinant Escherichia coli Colicin-Ib immunity Protein (aa 1-115)
VAng-Lsx02232-inquire inquire Ask for price
Description: Escherichia coli Colicin-Ib immunity protein, recombinant protein.

Recombinant Escherichia coli Colicin-Ia immunity Protein (aa 1-32)
VAng-Lsx02231-1mgEcoli 1 mg (E. coli)
EUR 3525.6
Description: Escherichia coli Colicin-Ia immunity protein (aa 1-32), recombinant protein.

Recombinant Escherichia coli Colicin-Ia immunity Protein (aa 1-32)
VAng-Lsx02231-500gEcoli 500 µg (E. coli)
EUR 2667.6
Description: Escherichia coli Colicin-Ia immunity protein (aa 1-32), recombinant protein.

Recombinant Human Innate immunity activator protein (INAVA)
CSB-YP662049HU 6526 mg Ask for price

Recombinant Escherichia coli Colicin-E5 immunity protein in ColE9 (aa 1-83)
VAng-Lsx02228-1mgEcoli 1 mg (E. coli)
EUR 3310.8
Description: Escherichia coli Colicin-E5 immunity protein in ColE9, recombinant protein.

Recombinant Escherichia coli Colicin-E5 immunity protein in ColE9 (aa 1-83)
VAng-Lsx02228-500gEcoli 500 µg (E. coli)
EUR 2353.2
Description: Escherichia coli Colicin-E5 immunity protein in ColE9, recombinant protein.

Recombinant Escherichia coli Colicin-E5 immunity protein in ColE9 (aa 1-83)
VAng-Lsx02228-50gEcoli 50 µg (E. coli)
EUR 1627.2
Description: Escherichia coli Colicin-E5 immunity protein in ColE9, recombinant protein.

Recombinant Human Immunity-related GTPase family M protein(IRGM)
AP76842 1mg
EUR 1978

Recombinant Human Immunity-related GTPase family M protein (IRGM)
CSB-EP011827HU 1511 mg Ask for price

IRGM Immunity-Related GTPase Family, M Human Recombinant Protein
PROTA1A4Y4 Regular: 20ug
EUR 380.4
Description: IRGM Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 180 amino acids (23-181) and having a molecular mass of 20.1 kDa. IRGM is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Recombinant Human Immunity-related GTPase family M protein Protein, GST, E.coli-1mg
QP6236-ec-1mg 1mg
EUR 1958.4

Recombinant Human Immunity-related GTPase family M protein Protein, GST, E.coli-100ug
QP6236-ec-100ug 100ug
EUR 489.6

Recombinant Human Immunity-related GTPase family M protein Protein, GST, E.coli-10ug
QP6236-ec-10ug 10ug
EUR 240

Recombinant Human Immunity-related GTPase family M protein Protein, GST, E.coli-200ug
QP6236-ec-200ug 200ug
EUR 760.8

Recombinant Human Immunity-related GTPase family M protein Protein, GST, E.coli-500ug
QP6236-ec-500ug 500ug
EUR 1272

Recombinant Human Immunity-related GTPase family M protein Protein, GST, E.coli-50ug
QP6236-ec-50ug 50ug
EUR 315.6

Immunity-Related GTPase Family, M Human Recombinant
rAP-3871 Inquiry Ask for price

Immunity-Related GTPase Family M Protein (IRGM) Protein
20-abx260986
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  • 1 mg
  • 20 ug
  • 5 ug

Immunity-Related GTPase Family M Protein (IRGM) Protein
abx260986-10g 10 µg
EUR 325

Immunity-Related GTPase Family M Protein (IRGM) Protein
abx260986-2g 2 µg
EUR 225

Human Immunity-related GTPase family M protein (IRGM)
1-CSB-EP011827HU
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  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Immunity-related GTPase family M protein(IRGM) expressed in E.coli

Human INAVA / Innate immunity activator protein ELISA Kit
E4998h 96T
EUR 736

Immunity-Related GTPase Family M Protein (IRGM) Antibody
20-abx126951
  • Ask for price
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  • 100 ul
  • 200 ul

Immunity-Related GTPase Family Q Protein (IRGQ) Antibody
abx032348-400ul 400 ul
EUR 661.2

Immunity-Related GTPase Family Q Protein (IRGQ) Antibody
abx032348-80l 80 µl
EUR 385.2

Immunity-Related GTPase Family M Protein (IRGM) Antibody
abx026104-400ul 400 ul
EUR 627.6

Immunity-Related GTPase Family M Protein (IRGM) Antibody
abx026104-80l 80 µl
EUR 343.2

Immunity-Related GTPase Family M Protein (IRGM) Antibody
20-abx210849
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  • 100 ul
  • 50 ul

Immunity-Related GTPase Family Q Protein (IRGQ) Antibody
abx234399-100ug 100 ug
EUR 661.2

Immunity-Related GTPase Family M Protein (IRGM) Antibody
abx448534-100ug 100 ug
EUR 627.6

Immunity-Related GTPase Family M Protein (IRGM) Antibody
20-abx321743
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  • 100 ul
  • 50 ul

Immunity-Related GTPase Family M Protein (IRGM) Antibody
20-abx339551
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  • 100 ul
  • 50 ul

Immunity-Related GTPase Family M Protein (IRGM) Antibody
abx210849-100l 100 µl
EUR 350

Immunity-Related GTPase Family M Protein (IRGM) Antibody
abx210849-50l 50 µl
EUR 250

Immunity-Related GTPase Family M Protein (IRGM) Antibody
abx026104-400l 400 µl
EUR 518.75

Immunity-Related GTPase Family Q Protein (IRGQ) Antibody
abx032348-400l 400 µl
EUR 518.75

Immunity-Related GTPase Family Q Protein (IRGQ) Antibody
abx234399-100g 100 µg
EUR 350

Immunity-Related GTPase Family M Protein (IRGM) Antibody
abx321743-100g 100 µg
EUR 350

Immunity-Related GTPase Family M Protein (IRGM) Antibody
abx321743-50g 50 µg
EUR 237.5

Immunity-Related GTPase Family M Protein (IRGM) Antibody
abx339551-100l 100 µl
EUR 350

Immunity-Related GTPase Family M Protein (IRGM) Antibody
abx339551-50l 50 µl
EUR 250

Immunity-Related GTPase Family M Protein (IRGM) Antibody
abx448534-1096tests 10 × 96 tests Ask for price

Immunity-Related GTPase Family M Protein (IRGM) Antibody
abx448534-596tests 5 × 96 tests Ask for price

Immunity-Related GTPase Family M Protein (IRGM) Antibody
abx448534-96tests 96 tests
EUR 550

Immunity-Related GTPase Family M Protein (IRGM) Antibody (PE)
abx448012-1096tests 10 × 96 tests Ask for price

Immunity-Related GTPase Family M Protein (IRGM) Antibody (PE)
abx448012-596tests 5 × 96 tests Ask for price

Immunity-Related GTPase Family M Protein (IRGM) Antibody (PE)
abx448012-96tests 96 tests
EUR 612.5

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ALP)
abx448005-100ug 100 ug
EUR 693.6

Immunity-Related GTPase Family M Protein (IRGM) Antibody (APC)
abx448006-100ug 100 ug
EUR 693.6

Immunity-Related GTPase Family M Protein (IRGM) Antibody (HRP)
abx448009-100ug 100 ug
EUR 678

Immunity-Related GTPase Family M Protein (IRGM) Antibody (RPE)
abx448012-100ug 100 ug
EUR 693.6

Immunity-Related GTPase Family M Protein (IRGM) Antibody (APC)
abx448006-1096tests 10 × 96 tests Ask for price

Immunity-Related GTPase Family M Protein (IRGM) Antibody (APC)
abx448006-596tests 5 × 96 tests Ask for price

Immunity-Related GTPase Family M Protein (IRGM) Antibody (APC)
abx448006-96tests 96 tests
EUR 612.5

Immunity-Related GTPase Family M Protein (IRGM) Antibody (HRP)
abx448009-1096tests 10 × 96 tests Ask for price

Immunity-Related GTPase Family M Protein (IRGM) Antibody (HRP)
abx448009-596tests 5 × 96 tests Ask for price

Immunity-Related GTPase Family M Protein (IRGM) Antibody (HRP)
abx448009-96tests 96 tests
EUR 600

Rat Immunity- related GTPase family M protein, Irgm ELISA KIT
ELI-20422r 96 Tests
EUR 1063.2

Immunity-Related GTPase Family M Protein (IRGM) Antibody (FITC)
abx448008-100ug 100 ug
EUR 678

Immunity-Related GTPase Family M Protein (IRGM) Antibody (FITC)
abx448008-1096tests 10 × 96 tests Ask for price

Immunity-Related GTPase Family M Protein (IRGM) Antibody (FITC)
abx448008-596tests 5 × 96 tests Ask for price

Immunity-Related GTPase Family M Protein (IRGM) Antibody (FITC)
abx448008-96tests 96 tests
EUR 600

Immunity-Related GTPase Family M Protein (IRGM) Antibody (PerCP)
abx448011-100ug 100 ug
EUR 693.6

Immunity-Related GTPase Family M Protein (IRGM) Antibody (PerCP)
abx448011-1096tests 10 × 96 tests Ask for price

Immunity-Related GTPase Family M Protein (IRGM) Antibody (PerCP)
abx448011-596tests 5 × 96 tests Ask for price

Immunity-Related GTPase Family M Protein (IRGM) Antibody (PerCP)
abx448011-96tests 96 tests
EUR 612.5

Human Immunity- related GTPase family Q protein, IRGQ ELISA KIT
ELI-13087h 96 Tests
EUR 988.8

Human Immunity- related GTPase family M protein, IRGM ELISA KIT
ELI-48787h 96 Tests
EUR 988.8

Mouse Immunity- related GTPase family Q protein, Irgq ELISA KIT
ELI-48788m 96 Tests
EUR 1038

Rat Immunity-Related GTPase Family M Protein (IRGM) ELISA Kit
abx528647-96tests 96 tests
EUR 687.5

Immunity-Related GTPase Family M Protein (IRGM) Antibody (Biotin)
abx448007-100ug 100 ug
EUR 693.6

Immunity-Related GTPase Family M Protein (IRGM) Antibody (Biotin)
abx448007-1096tests 10 × 96 tests Ask for price

Immunity-Related GTPase Family M Protein (IRGM) Antibody (Biotin)
abx448007-596tests 5 × 96 tests Ask for price

Immunity-Related GTPase Family M Protein (IRGM) Antibody (Biotin)
abx448007-96tests 96 tests
EUR 600

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO390)
abx447997-1096tests 10 × 96 tests Ask for price

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO390)
abx447997-596tests 5 × 96 tests Ask for price

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO390)
abx447997-96tests 96 tests
EUR 612.5

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO488)
abx447998-1096tests 10 × 96 tests Ask for price

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO488)
abx447998-596tests 5 × 96 tests Ask for price

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO488)
abx447998-96tests 96 tests
EUR 612.5

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO594)
abx448000-1096tests 10 × 96 tests Ask for price

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO594)
abx448000-596tests 5 × 96 tests Ask for price

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO594)
abx448000-96tests 96 tests
EUR 612.5

Human Immunity-Related GTPase Family Q Protein (IRGQ) ELISA Kit
abx388031-96tests 96 tests
EUR 1093.2

Human Immunity-related GTPase family M protein (IRGM) ELISA Kit
abx528646-96tests 96 tests
EUR 687.5

Mouse Immunity-related GTPase family Q protein (IRGQ) ELISA Kit
abx528650-96tests 96 tests
EUR 687.5

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO 390)
abx447997-100ug 100 ug
EUR 693.6

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO 488)
abx447998-100ug 100 ug
EUR 693.6

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO 565)
abx447999-100ug 100 ug
EUR 693.6

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO 594)
abx448000-100ug 100 ug
EUR 693.6

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO 633)
abx448001-100ug 100 ug
EUR 693.6

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO 655)
abx448002-100ug 100 ug
EUR 693.6

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO 680)
abx448003-100ug 100 ug
EUR 693.6

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO 700)
abx448004-100ug 100 ug
EUR 693.6

Mouse Immunity- related GTPase family M protein 1, Irgm1 ELISA K
ELI-43703m 96 Tests
EUR 1038

Immunity-Related GTPase Family M Protein (IRGM) Antibody (Streptavidin)
abx448013-100ug 100 ug
EUR 693.6

Immunity-Related GTPase Family M Protein (IRGM) Antibody (PE/ATTO 594)
abx448010-100ug 100 ug
EUR 710.4

Mouse Immunity-related GTPase family M protein 1 (IRGM1) ELISA Kit
abx528648-96tests 96 tests
EUR 687.5

Human Tumor Immunity Primer Library
HTIMU-I 1 set
EUR 657.6

Mouse Tumor Immunity Primer Library
MTIMU-I 1 set
EUR 657.6

Immunity Related GTPase M (IRGM) Antibody
abx412110-01mg 0.1 mg
EUR 644.4

Immunity Related GTPase M (IRGM) Antibody
abx412110-100tests 100 tests
EUR 537.5

IRGQ (untagged)-Human immunity-related GTPase family, Q (IRGQ)
SC301246 10 µg Ask for price

Rat Low Density Lipoprotein Immunity Complex (LDL-IC) CLIA Kit
abx197236-96tests 96 tests
EUR 990

IRGC (untagged)-Human immunity-related GTPase family, cinema (IRGC)
SC304683 10 µg Ask for price

IRGQ (GFP-tagged) - Human immunity-related GTPase family, Q (IRGQ)
RG219583 10 µg Ask for price

IRGM (GFP-tagged) - Human immunity-related GTPase family, M (IRGM)
RG227287 10 µg Ask for price

Irgq (untagged) - Mouse immunity-related GTPase family, Q (Irgq), (10ug)
MC219334 10 µg Ask for price

IRGM (untagged)-Human immunity-related GTPase family, M (IRGM), mRNA
SC326449 10 µg Ask for price

CLIA kit for Rat LDL-IC (Low Density Lipoprotein Immunity Complex)
E-CL-R0415 1 plate of 96 wells
EUR 700.8
Description: A sandwich CLIA kit for quantitative measurement of Rat LDL-IC (Low Density Lipoprotein Immunity Complex) in samples from Serum, Plasma, Cell supernatant

LDL-IC ELISA Kit| Rat Low Density Lipoprotein Immunity Complex E
EF017860 96 Tests
EUR 826.8

IRGC (GFP-tagged) - Human immunity-related GTPase family, cinema (IRGC)
RG209793 10 µg Ask for price

ELISA kit for Rat LDL-IC (Low Density Lipoprotein Immunity Complex)
E-EL-R0581 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Rat LDL-IC (Low Density Lipoprotein Immunity Complex) in samples from Serum, Plasma, Cell supernatant

Irgm (untagged ORF) - Rat immunity-related GTPase family, M (Irgm), (10 ug)
RN208492 10 µg Ask for price

Irgq (untagged ORF) - Rat immunity-related GTPase family, Q (Irgq), (10 ug)
RN205706 10 µg Ask for price

Irgq (Myc-DDK-tagged) - Mouse immunity-related GTPase family, Q (Irgq)
MR209126 10 µg Ask for price

IRGM (Myc-DDK-tagged)-Human immunity-related GTPase family, M (IRGM)
RC227287 10 µg Ask for price

IRGQ (Myc-DDK-tagged)-Human immunity-related GTPase family, Q (IRGQ)
RC219583 10 µg Ask for price

IL-24 Recombinant Protein
90-527 25 ug
EUR 682.8
Description: IL-24 is a cytokine belonging to the IL-10 family of cytokines that signals through two heterodimeric receptors: IL-20R1/IL-20R2 and IL-22R1/IL-20R2. This interleukin is also known as melanoma differentiation-associated 7 (mda-7) due to its discovery as a tumour suppressing protein. IL-24 appears to control cell survival and proliferation by inducing rapid activation of particular transcription factors called STAT1 and STAT3. It is predominantly released by activated monocytes, macrophages and T helper 2 (Th2) cells and acts on non-haematopoietic tissues such as skin, lung and reproductive tissues. IL-24 performs important roles in wound healing, psoriasis and cancer. IL-24 has antiproliferative properties is inhibiting angiogenesis and may contribute to terminal cell differentiation.

IL-24 Recombinant Protein
40-600-0005mg 0.005 mg
EUR 311.1
Description: IL-24 is a secreted glycoprotein belonging to the IL-10 structural family of cytokines. It is produced by a variety of cell types, including B cells, CD4+ cells, NK cells, lymph node DCs, monocytes, and melanoma cells. IL-24 can signal through the IL20R1/IL20R2 and IL22R1/IL20R2 receptors to initiate a signaling cascade which includes the induction of JAK1/STAT3 phosphorylation. IL-24 is, functionally, a pleiotropic protein but is generally characterized as an anti-cancer cytokine that can selectively inhibit growth of a wide variety of human cancer cells through activities that include the induction of differentiation and apoptosis, and the suppression of angiogenesis and cell proliferation. Recombinant human IL-24 is an 18.9 kDa glycoprotein, containing 161 amino acid residues, including a C-terminal His-tag.

IL-24 Recombinant Protein
40-600-002mg 0.02 mg
EUR 437.1
Description: IL-24 is a secreted glycoprotein belonging to the IL-10 structural family of cytokines. It is produced by a variety of cell types, including B cells, CD4+ cells, NK cells, lymph node DCs, monocytes, and melanoma cells. IL-24 can signal through the IL20R1/IL20R2 and IL22R1/IL20R2 receptors to initiate a signaling cascade which includes the induction of JAK1/STAT3 phosphorylation. IL-24 is, functionally, a pleiotropic protein but is generally characterized as an anti-cancer cytokine that can selectively inhibit growth of a wide variety of human cancer cells through activities that include the induction of differentiation and apoptosis, and the suppression of angiogenesis and cell proliferation. Recombinant human IL-24 is an 18.9 kDa glycoprotein, containing 161 amino acid residues, including a C-terminal His-tag.

Irgc1 (untagged) - Mouse immunity-related GTPase family, cinema 1 (Irgc1), (10ug)
MC216366 10 µg Ask for price

IRGC (Myc-DDK-tagged)-Human immunity-related GTPase family, cinema (IRGC)
RC209793 10 µg Ask for price

Beta 2 microglobulin Recombinant Protein
96-039 0.1 mg
EUR 588.3
Description: β2 microglobulin is also known as Beta-2-microglobulin (B2M), is a component of MHC class I molecules which belongs to the beta-2-microglobulin family. B2M is present on all nucleated cells (excludes red blood cells). B2M associates not only with the alpha chain of MHC class I molecules, but also with class I-like molecules such as CD1 and Qa. An additional function of B2M is association with the HFE protein, together regulating the expression of hepcidin in the liver which targets the iron transporter ferroportin on the cytoplasmic membrane of enterocytes and macrophages for degradation resulting in decreased iron uptake from food and iron release from recycled red blood cells respectively. Loss of this function causes iron excess and hemochromatosis. Defects in B2M are the cause of hypercatabolic hypoproteinemia (HYCATHYP).

Beta 2 microglobulin Recombinant Protein
96-040 0.1 mg
EUR 588.3
Description: β2 microglobulin is also known as Beta-2-microglobulin (B2M), is a component of MHC class I molecules which belongs to the beta-2-microglobulin family. B2M is present on all nucleated cells (excludes red blood cells). B2M associates not only with the alpha chain of MHC class I molecules, but also with class I-like molecules such as CD1 and Qa. An additional function of B2M is association with the HFE protein, together regulating the expression of hepcidin in the liver which targets the iron transporter ferroportin on the cytoplasmic membrane of enterocytes and macrophages for degradation resulting in decreased iron uptake from food and iron release from recycled red blood cells respectively. Loss of this function causes iron excess and hemochromatosis. Defects in B2M are the cause of hypercatabolic hypoproteinemia (HYCATHYP).

Beta 2 microglobulin Recombinant Protein
96-042 0.05 mg
EUR 619.8
Description: β2 microglobulin is also known as Beta-2-microglobulin (B2M), is a component of MHC class I molecules which belongs to the beta-2-microglobulin family. B2M is present on all nucleated cells (excludes red blood cells). B2M associates not only with the alpha chain of MHC class I molecules, but also with class I-like molecules such as CD1 and Qa. An additional function of B2M is association with the HFE protein, together regulating the expression of hepcidin in the liver which targets the iron transporter ferroportin on the cytoplasmic membrane of enterocytes and macrophages for degradation resulting in decreased iron uptake from food and iron release from recycled red blood cells respectively. Loss of this function causes iron excess and hemochromatosis. Defects in B2M are the cause of hypercatabolic hypoproteinemia (HYCATHYP).

Recombinant Toxoplasma Gondii MIC6 Protein (aa 24-349)
VAng-0441Lsx-100g 100 µg
EUR 7929.6
Description: Toxoplasma Gondii Micronemal protein 6, recombinant protein.

Recombinant Toxoplasma Gondii MIC6 Protein (aa 24-349)
VAng-0441Lsx-50g 50 µg
EUR 4876.8
Description: Toxoplasma Gondii Micronemal protein 6, recombinant protein.

Irgc1 (GFP-tagged) - Mouse immunity-related GTPase family cinema 1 (Irgc1), (10ug)
MG217095 10 µg Ask for price

Irgm2 (untagged) - Mouse immunity-related GTPase family M member 2 (Irgm2), (10ug)
MC208056 10 µg Ask for price

Irgm1 (untagged) - Mouse immunity-related GTPase family M member 1 (Irgm1), (10ug)
MC208739 10 µg Ask for price

Lenti ORF clone of Human immunity-related GTPase family, Q (IRGQ), mGFP tagged
RC219583L2 10 µg Ask for price

Lenti ORF clone of Human immunity-related GTPase family, Q (IRGQ), mGFP tagged
RC219583L4 10 µg Ask for price

Recombinant Microtubule Associated Protein 4 (MAP4)
RPB319Hu01 10ug
EUR 162

Recombinant Microtubule Associated Protein 4 (MAP4)
4-RPB319Hu01
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  • Ask for price
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Microtubule Associated Protein 4 expressed in: E.coli

Recombinant Microtubule Associated Protein 4 (MAP4)
RPB319Mu01 10ug
EUR 176

Recombinant Microtubule Associated Protein 4 (MAP4)
4-RPB319Mu01
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  • 100 ug
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  • 50ug
  • 5 mg
Description: Recombinant Mouse Microtubule Associated Protein 4 expressed in: E.coli

Recombinant Microtubule Associated Protein 4 (MAP4)
RPB319Ra01 10ug
EUR 184

Recombinant Microtubule Associated Protein 4 (MAP4)
4-RPB319Ra01
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  • 5 mg
Description: Recombinant Rat Microtubule Associated Protein 4 expressed in: E.coli

Recombinant Microtubule Associated Protein 2 (MAP2)
RPB329Hu01 10ug
EUR 168

Recombinant Microtubule Associated Protein 2 (MAP2)
4-RPB329Hu01
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Description: Recombinant Human Microtubule Associated Protein 2 expressed in: E.coli

Recombinant Microtubule Associated Protein 2 (MAP2)
RPB329Mu01 10ug
EUR 176

Recombinant Microtubule Associated Protein 2 (MAP2)
4-RPB329Mu01
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  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Mouse Microtubule Associated Protein 2 expressed in: E.coli

Recombinant Microtubule Associated Protein 2 (MAP2)
RPB329Ra01 10ug
EUR 184

Recombinant Microtubule Associated Protein 2 (MAP2)
4-RPB329Ra01
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  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
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  • 50ug
  • 5 mg
Description: Recombinant Rat Microtubule Associated Protein 2 expressed in: E.coli

Recombinant Microtubule Associated Protein 6 (MAP6)
RPB335Mu01 10ug
EUR 179

Recombinant Microtubule Associated Protein 6 (MAP6)
4-RPB335Mu01
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  • 100 ug
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  • 1 mg
  • 200 ug
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  • 50ug
  • 5 mg
Description: Recombinant Mouse Microtubule Associated Protein 6 expressed in: E.coli

Recombinant Microtubule Associated Protein 9 (MAP9)
RPU58261-100ug 100ug
EUR 537.6

Recombinant Microtubule Associated Protein 9 (MAP9)
RPU58261-1mg 1mg
EUR 2496

Recombinant Microtubule Associated Protein 9 (MAP9)
RPU58261-50ug 50ug
EUR 418

Recombinant Microtubule Associated Protein 2 (MAP2)
RPU56943-100ug 100ug
EUR 470.4

Antiviral brokers similar to human sera containing NAbs or antiviral interferons dose dependently lowered the SARS-CoV-2-specific sign. Applying elevated infectious doses, the icELISA-based neutralization take a look at (icNT) was superior to PRNT in discriminating convalescent sera with excessive from these with intermediate neutralizing capacities. In addition, the icNT was discovered to be particular, discriminating between SARS-CoV-2-specific NAbs and these raised in opposition to different coronaviruses. Altogether, the SARS-CoV-2 icELISA take a look at permits fast (<48 h in complete, read-out in seconds) and automated quantification of virus an infection in cell tradition to guage the efficacy of NAbs and antiviral medicine utilizing reagents and tools current in most routine diagnostics departments.

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