CD4+T cell epitopes performs a key position in anti-tuberculosis (TB) immunity, CD4+T cell epitopes appropriate for the home inhabitants are missing. Therefore, we predicted and recognized novel CD4+T cell epitopes.The bioinformatics software program, specifically, DNAStar (DNASTAR of the United States), SYFPEITHI (INTERFACTORS INSTITUT Für ZELL Biologie of Germany), RANKPEP, and NetMHC IIpan (National Cancer Institute, United States of America), have been used to comprehensively predict the CD4+T cell immune epitope of Mycobacterium TB, and the predicted epitope polypeptide was synthesized by the commonplace Fmoc scheme. The proliferation of PBMC and CD4+T cells stimulated by peptides was preliminarily detected by the CCK8 technique.
Then, the candidate polypeptides screened out by the CCK8 technique have been verified once more by the BrdU assay, and movement cytometry was carried out to investigate additional the extent of their stimulation on the proliferation of CD4+T cells. The adjustments in the secreted cytokines IFN-γ, TNF-α, IL-2, and IL-10 earlier than and after the candidate polypeptide stimulation of CD4+T lymphocytes have been detected by ELISA. The preliminary humoral immunity take a look at was carried out by oblique ELISA to judge the serological diagnostic worth of the CD4+T cell epitope polypeptide.
In this research, 5 novel candidate CD4+T cell epitope polypeptides with the amino acid sequences of LQGQWRGAAGTAAQA, PVTLAETGSTLLYPL, AAAWGGSGSEAYQGV, QFVYAGAMSGLLDPS, and KAALTRTASNMNAAA and others that haven’t been reported in the analysis have been predicted. For comfort, the 5 candidates have been successively named as P39, P50, P40, P185, and P62. P39, P62, and the blended peptide P39+P62 may successfully induce the proliferation of CD4+T cells and improve the secretion of IFN-γ, TNF-α, and IL-2 from the CD4+T cells, whereas lowering the content material of IL-10.
The serological take a look at confirmed that the sensitivity, specificity, and space below the receiver working attribute curve (AUC) of P39 have been 75%, 67.71%, and 0.844, respectively. The sensitivity, specificity, and AUC of P62 have been 91.66%, 46.87%, and 0.649, respectively. The sensitivity of the blended peptide P39+P62 was 95.83%, the specificity was 97.91%, and the AUC was 0.793.The P39 and P62 polypeptides have been predicted and recognized as potential CD4+T cell immune epitope polypeptides of M. TB. The polypeptide had higher analysis impact, which offered potential candidate epitope polypeptides for the growth of TB-specific analysis reagents and novel TB epitope vaccines.
Dietary Chitosan Nanoparticles: Potential Role in Modulation of Rainbow Trout ( Oncorhynchus mykiss) Antibacterial Defense and Intestinal Immunity in opposition to Enteric Redmouth Disease
Bio-nanotechnology using bio-sourced nanomaterial is an rising avenue serving the area of fish drugs. Marine-sourced chitosan nanoparticles (CSNPs) is a widely known antimicrobial and immunomodulatory reagent with low or no hurt uncomfortable side effects on fish or their human customers. In this research, in vitro pores and skin mucus and serum antibacterial exercise assays together with intestinal histology, histochemical, and gene expression analyses have been carried out to judge the impression of dietary CSNPs (5 g kg-1 dry feed) on rainbow trout resistance in opposition to ‘enteric redmouth’ illness. Two therapy situations have been included; short-term prophylactic-regimen for 21 days earlier than the bacterial problem, and long-term therapeutic-regimen for 21 days earlier than the problem and prolonged for 28 days after the problem.
Our outcomes revealed larger antibacterial protection means and optimistic intestinal histochemical and molecular traits of rainbow trout after dietary CSNPs. The prophylactic-regimen improved trout well being whereas the therapeutic routine improved their illness resistance and lowered their morbidity. Therefore, it’s anticipated that CSNPs is an efficient antibacterial and immunomodulatory fish feed complement in opposition to the infectious threats. However, the CSNPs appear to be simpler in the therapeutic utility relatively than getting used for short-term prophylactic purposes.
The Koala Immune Response to Chlamydial Infection and Vaccine Development-Advancing Our Immunological Understanding
Chlamydia is a major pathogen for many species, together with the much-loved Australian marsupial, the koala (Phascolarctos cinereus). To fight this case, centered analysis has gone into the growth and refinement of a chlamydial vaccine for koalas. The basis of this course of has concerned characterising the immune response of koalas to each pure chlamydial an infection in addition to vaccination. From parallels in human and mouse analysis, it’s well-established that an efficient anti-chlamydial response will contain a stability of cell-mediated Th1 responses involving interferon-gamma (IFN-γ), humoral Th2 responses involving systemic IgG and mucosal IgA, and inflammatory Th17 responses involving interleukin 17 (IL-17) and neutrophils.
Characterisation of koalas with chlamydial illness has proven elevated expression inside all three of these main immunological pathways and monitoring of koalas’ post-vaccination has detected additional enhancements to those key pathways. These findings supply optimism {that a} chlamydial vaccine for wider distribution to koalas just isn’t far off. Recent advances in marsupial genetic data and normal nucleic acid assay expertise have moved koala immunological analysis a step nearer to different mammalian analysis techniques. However, koala-specific reagents to instantly assay cytokine ranges and cell-surface markers are nonetheless wanted to progress our understanding of koala immunology.
Recombinant Escherichia coli Colicin-Ia immunity Protein (aa 1-111) |
VAng-Lsx02230-inquire |
Creative Biolabs |
inquire |
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Description: Escherichia coli Colicin-Ia immunity protein, recombinant protein. |
Recombinant Escherichia coli Colicin-Ib immunity Protein (aa 1-115) |
VAng-Lsx02232-inquire |
Creative Biolabs |
inquire |
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Description: Escherichia coli Colicin-Ib immunity protein, recombinant protein. |
Recombinant Escherichia coli Colicin-Ia immunity Protein (aa 1-32) |
VAng-Lsx02231-1mgEcoli |
Creative Biolabs |
1 mg (E. coli) |
EUR 3525.6 |
Description: Escherichia coli Colicin-Ia immunity protein (aa 1-32), recombinant protein. |
Recombinant Escherichia coli Colicin-Ia immunity Protein (aa 1-32) |
VAng-Lsx02231-500gEcoli |
Creative Biolabs |
500 µg (E. coli) |
EUR 2667.6 |
Description: Escherichia coli Colicin-Ia immunity protein (aa 1-32), recombinant protein. |
KRIBIOLISA Protein A ELISA (natural & structurally conserved recombinant Protein A specific) |
KBBP12 |
Krishgen |
1 x 96 wells |
EUR 385 |
Recombinant Escherichia coli Colicin-E5 immunity protein in ColE9 (aa 1-83) |
VAng-Lsx02228-1mgEcoli |
Creative Biolabs |
1 mg (E. coli) |
EUR 3310.8 |
Description: Escherichia coli Colicin-E5 immunity protein in ColE9, recombinant protein. |
Recombinant Escherichia coli Colicin-E5 immunity protein in ColE9 (aa 1-83) |
VAng-Lsx02228-500gEcoli |
Creative Biolabs |
500 µg (E. coli) |
EUR 2353.2 |
Description: Escherichia coli Colicin-E5 immunity protein in ColE9, recombinant protein. |
Recombinant Escherichia coli Colicin-E5 immunity protein in ColE9 (aa 1-83) |
VAng-Lsx02228-50gEcoli |
Creative Biolabs |
50 µg (E. coli) |
EUR 1627.2 |
Description: Escherichia coli Colicin-E5 immunity protein in ColE9, recombinant protein. |
Recombinant Human Immunity-related GTPase family M protein (IRGM) |
CSB-EP011827HU |
Cusabio |
1511 mg |
Ask for price |
Recombinant Human Immunity-related GTPase family M protein(IRGM) |
AP76842 |
SAB |
1mg |
EUR 1978 |
|
IRGM Immunity-Related GTPase Family, M Human Recombinant Protein |
PROTA1A4Y4 |
BosterBio |
Regular: 20ug |
EUR 380.4 |
Description: IRGM Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 180 amino acids (23-181) and having a molecular mass of 20.1 kDa. IRGM is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
Recombinant Human Antiviral innate immune response receptor RIG-I (RIGI), partial |
CSB-EP006638HU |
Cusabio |
1009 mg |
Ask for price |
Recombinant Human Antiviral innate immune response receptor RIG-I (DDX58) ,partial |
RPC21200-100ug |
Biomatik Corporation |
100ug |
EUR 460.9 |
Recombinant Human Antiviral innate immune response receptor RIG-I (DDX58) ,partial |
RPC21200-1mg |
Biomatik Corporation |
1mg |
EUR 2237.8 |
Recombinant Human Antiviral innate immune response receptor RIG-I (DDX58) ,partial |
RPC21200-20ug |
Biomatik Corporation |
20ug |
EUR 258.7 |
Recombinant Regulator Of G Protein Signaling 3 (RGS3) |
RPU53976-100ug |
Biomatik Corporation |
100ug |
EUR 566.5 |
Recombinant Regulator Of G Protein Signaling 3 (RGS3) |
RPU53976-1mg |
Biomatik Corporation |
1mg |
EUR 2511.6 |
Recombinant Regulator Of G Protein Signaling 3 (RGS3) |
RPU53976-50ug |
Biomatik Corporation |
50ug |
EUR 455.4 |
Recombinant Regulator Of G Protein Signaling 3 (RGS3) |
RPD703Mu01 |
Cloud-Clone |
10ug |
EUR 184 |
Recombinant Regulator Of G Protein Signaling 3 (RGS3) |
4-RPD703Mu01 |
Cloud-Clone |
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|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Mouse Regulator Of G Protein Signaling 3 expressed in: E.coli |
Recombinant Human Immunity-related GTPase family M protein Protein, GST, E.coli-1mg |
QP6236-ec-1mg |
EnQuireBio |
1mg |
EUR 1958.4 |
Recombinant Human Immunity-related GTPase family M protein Protein, GST, E.coli-100ug |
QP6236-ec-100ug |
EnQuireBio |
100ug |
EUR 489.6 |
Recombinant Human Immunity-related GTPase family M protein Protein, GST, E.coli-10ug |
QP6236-ec-10ug |
EnQuireBio |
10ug |
EUR 240 |
Recombinant Human Immunity-related GTPase family M protein Protein, GST, E.coli-200ug |
QP6236-ec-200ug |
EnQuireBio |
200ug |
EUR 760.8 |
Recombinant Human Immunity-related GTPase family M protein Protein, GST, E.coli-500ug |
QP6236-ec-500ug |
EnQuireBio |
500ug |
EUR 1272 |
Recombinant Human Immunity-related GTPase family M protein Protein, GST, E.coli-50ug |
QP6236-ec-50ug |
EnQuireBio |
50ug |
EUR 315.6 |
Recombinant human Conserved oligomeric Golgi complex subunit 6 |
P2345 |
FN Test |
100ug |
Ask for price |
|
Description: Recombinant protein for human Conserved oligomeric Golgi complex subunit 6 |
RCAN3 Regulator of Calcineurin 3 Human Recombinant Protein |
PROTQ9UKA8 |
BosterBio |
Regular: 10ug |
EUR 380.4 |
Description: RCAN3 Human Recombinant produced in E. coli is a single polypeptide chain containing 209 amino acids (56-241) and having a molecular mass of 23.5 kDa. RCAN3 is fused to 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
Immunity-Related GTPase Family, M Human Recombinant |
rAP-3871 |
Angio Proteomie |
Inquiry |
Ask for price |
Recombinant T-Cell, Immune Regulator 1 (TCIRG1) |
RPM347Hu01 |
Cloud-Clone |
10ug |
EUR 140 |
Recombinant Regulator Of G Protein Signaling 9 (RGS9) |
RPU51070-100ug |
Biomatik Corporation |
100ug |
EUR 455.4 |
Recombinant Regulator Of G Protein Signaling 9 (RGS9) |
RPU51070-1mg |
Biomatik Corporation |
1mg |
EUR 2020.2 |
Recombinant Regulator Of G Protein Signaling 9 (RGS9) |
RPU51070-50ug |
Biomatik Corporation |
50ug |
EUR 366.3 |
Recombinant Regulator Of G Protein Signaling 7 (RGS7) |
RPU53624-100ug |
Biomatik Corporation |
100ug |
EUR 554.4 |
Recombinant Regulator Of G Protein Signaling 7 (RGS7) |
RPU53624-1mg |
Biomatik Corporation |
1mg |
EUR 2457 |
Recombinant Regulator Of G Protein Signaling 7 (RGS7) |
RPU53624-50ug |
Biomatik Corporation |
50ug |
EUR 445.5 |
Recombinant Regulator Of G Protein Signaling 9 (RGS9) |
RPD699Hu01 |
Cloud-Clone |
10ug |
EUR 148 |
Recombinant Regulator Of G Protein Signaling 9 (RGS9) |
4-RPD699Hu01 |
Cloud-Clone |
-
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-
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-
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|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Human Regulator Of G Protein Signaling 9 expressed in: E.coli |
Recombinant Regulator Of G Protein Signaling 9 (RGS9) |
RPD699Mu01 |
Cloud-Clone |
10ug |
EUR 156 |
Recombinant Regulator Of G Protein Signaling 9 (RGS9) |
4-RPD699Mu01 |
Cloud-Clone |
-
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|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Mouse Regulator Of G Protein Signaling 9 expressed in: E.coli |
Recombinant Regulator Of G Protein Signaling 1 (RGS1) |
RPD701Hu01 |
Cloud-Clone |
10ug |
EUR 160 |
Recombinant Regulator Of G Protein Signaling 1 (RGS1) |
4-RPD701Hu01 |
Cloud-Clone |
-
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-
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-
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|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Human Regulator Of G Protein Signaling 1 expressed in: E.coli |
Recombinant Regulator Of G Protein Signaling 5 (RGS5) |
RPD705Mu01 |
Cloud-Clone |
10ug |
EUR 176 |
Recombinant Regulator Of G Protein Signaling 5 (RGS5) |
4-RPD705Mu01 |
Cloud-Clone |
-
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-
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-
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-
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-
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-
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|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Mouse Regulator Of G Protein Signaling 5 expressed in: E.coli |
Recombinant Regulator Of G Protein Signaling 6 (RGS6) |
RPD706Hu01 |
Cloud-Clone |
10ug |
EUR 160 |
Recombinant Regulator Of G Protein Signaling 6 (RGS6) |
RPD706Ra01 |
Cloud-Clone |
10ug |
EUR 194 |
Recombinant Regulator Of G Protein Signaling 6 (RGS6) |
4-RPD706Ra01 |
Cloud-Clone |
-
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-
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-
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-
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|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Rat Regulator Of G Protein Signaling 6 expressed in: E.coli |
Recombinant Regulator Of G Protein Signaling 7 (RGS7) |
RPD707Hu01 |
Cloud-Clone |
10ug |
EUR 180 |
Recombinant Regulator Of G Protein Signaling 7 (RGS7) |
4-RPD707Hu01 |
Cloud-Clone |
-
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-
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-
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-
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|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Human Regulator Of G Protein Signaling 7 expressed in: E.coli |
Recombinant Regulator Of G Protein Signaling 8 (RGS8) |
RPD708Hu01 |
Cloud-Clone |
10ug |
EUR 160 |
Recombinant Regulator Of G Protein Signaling 4 (RGS4) |
RPU43585-100ug |
Biomatik Corporation |
100ug |
EUR 591.8 |
Recombinant Regulator Of G Protein Signaling 4 (RGS4) |
RPU43585-1mg |
Biomatik Corporation |
1mg |
EUR 2620.8 |
Recombinant Regulator Of G Protein Signaling 4 (RGS4) |
RPU43585-50ug |
Biomatik Corporation |
50ug |
EUR 475.2 |
Recombinant Regulator Of G Protein Signaling 5 (RGS5) |
RPU53142-100ug |
Biomatik Corporation |
100ug |
EUR 542.3 |
Recombinant Regulator Of G Protein Signaling 5 (RGS5) |
RPU53142-1mg |
Biomatik Corporation |
1mg |
EUR 2402.4 |
Recombinant Regulator Of G Protein Signaling 5 (RGS5) |
RPU53142-50ug |
Biomatik Corporation |
50ug |
EUR 435.6 |
Recombinant Regulator Of G Protein Signaling 9 (RGS9) |
RPU51388-100ug |
Biomatik Corporation |
100ug |
EUR 480.7 |
Recombinant Regulator Of G Protein Signaling 9 (RGS9) |
RPU51388-1mg |
Biomatik Corporation |
1mg |
EUR 2129.4 |
Recombinant Regulator Of G Protein Signaling 9 (RGS9) |
RPU51388-50ug |
Biomatik Corporation |
50ug |
EUR 386.1 |
Recombinant Regulator Of G Protein Signaling 1 (RGS1) |
RPU51592-100ug |
Biomatik Corporation |
100ug |
EUR 492.8 |
Recombinant Regulator Of G Protein Signaling 1 (RGS1) |
RPU51592-1mg |
Biomatik Corporation |
1mg |
EUR 2184 |
Recombinant Regulator Of G Protein Signaling 1 (RGS1) |
RPU51592-50ug |
Biomatik Corporation |
50ug |
EUR 396 |
Recombinant Regulator Of G Protein Signaling 5 (RGS5) |
RPU57233-100ug |
Biomatik Corporation |
100ug |
EUR 470.4 |
Recombinant Regulator Of G Protein Signaling 5 (RGS5) |
RPU57233-1mg |
Biomatik Corporation |
1mg |
EUR 2184 |
Recombinant Regulator Of G Protein Signaling 5 (RGS5) |
RPU57233-50ug |
Biomatik Corporation |
50ug |
EUR 385 |
Recombinant Regulator Of G Protein Signaling 6 (RGS6) |
RPU58049-100ug |
Biomatik Corporation |
100ug |
EUR 537.6 |
Recombinant Regulator Of G Protein Signaling 6 (RGS6) |
RPU58049-1mg |
Biomatik Corporation |
1mg |
EUR 2496 |
Recombinant Regulator Of G Protein Signaling 6 (RGS6) |
RPU58049-50ug |
Biomatik Corporation |
50ug |
EUR 418 |
Recombinant Regulator Of G Protein Signaling 8 (RGS8) |
RPU58050-100ug |
Biomatik Corporation |
100ug |
EUR 537.6 |
Recombinant Regulator Of G Protein Signaling 8 (RGS8) |
RPU58050-1mg |
Biomatik Corporation |
1mg |
EUR 2496 |
Recombinant Regulator Of G Protein Signaling 8 (RGS8) |
RPU58050-50ug |
Biomatik Corporation |
50ug |
EUR 418 |
Recombinant Regulator Of G Protein Signaling 6 (RGS6) |
RPU54442-100ug |
Biomatik Corporation |
100ug |
EUR 599.5 |
Recombinant Regulator Of G Protein Signaling 6 (RGS6) |
RPU54442-1mg |
Biomatik Corporation |
1mg |
EUR 2653.3 |
Recombinant Regulator Of G Protein Signaling 6 (RGS6) |
RPU54442-50ug |
Biomatik Corporation |
50ug |
EUR 480.7 |
Recombinant Regulator Of G Protein Signaling 4 (RGS4) |
RPA978Hu01 |
Cloud-Clone |
10ug |
EUR 192 |
Recombinant Regulator Of G Protein Signaling 4 (RGS4) |
4-RPA978Hu01 |
Cloud-Clone |
-
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|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Human Regulator Of G Protein Signaling 4 expressed in: E.coli |
Recombinant Regulator Of G Protein Signaling 10 (RGS10) |
RPU51005-100ug |
Biomatik Corporation |
100ug |
EUR 443.3 |
Recombinant Regulator Of G Protein Signaling 10 (RGS10) |
RPU51005-1mg |
Biomatik Corporation |
1mg |
EUR 1965.6 |
Recombinant Regulator Of G Protein Signaling 10 (RGS10) |
RPU51005-50ug |
Biomatik Corporation |
50ug |
EUR 356.4 |
Recombinant Regulator Of G Protein Signaling 19 (RGS19) |
RPU53712-100ug |
Biomatik Corporation |
100ug |
EUR 554.4 |
Recombinant Regulator Of G Protein Signaling 19 (RGS19) |
RPU53712-1mg |
Biomatik Corporation |
1mg |
EUR 2457 |
Recombinant Regulator Of G Protein Signaling 19 (RGS19) |
RPU53712-50ug |
Biomatik Corporation |
50ug |
EUR 445.5 |
Recombinant Regulator Of G Protein Signaling 10 (RGS10) |
RPD700Mu01 |
Cloud-Clone |
10ug |
EUR 144 |
Recombinant Regulator Of G Protein Signaling 10 (RGS10) |
4-RPD700Mu01 |
Cloud-Clone |
-
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|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Mouse Regulator Of G Protein Signaling 10 expressed in: E.coli |
Recombinant Regulator Of G Protein Signaling 20 (RGS20) |
RPU59538-100ug |
Biomatik Corporation |
100ug |
EUR 604.8 |
Recombinant Regulator Of G Protein Signaling 20 (RGS20) |
RPU59538-1mg |
Biomatik Corporation |
1mg |
EUR 2632.5 |
Recombinant Regulator Of G Protein Signaling 20 (RGS20) |
RPU59538-50ug |
Biomatik Corporation |
50ug |
EUR 539 |
Recombinant Regulator Of G Protein Signaling 20 (RGS20) |
RPP227Hu01 |
Cloud-Clone |
10ug |
EUR 180 |
Recombinant Regulator Of G Protein Signaling 19 (RGS19) |
RPP367Hu01 |
Cloud-Clone |
10ug |
EUR 180 |
Recombinant Regulator Of G Protein Signaling 19 (RGS19) |
4-RPP367Hu01 |
Cloud-Clone |
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|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
Description: Recombinant Human Regulator Of G Protein Signaling 19 expressed in: E.coli |
Recombinant Human Regulator of microtubule dynamics protein 3 (RMDN3) |
CSB-EP836307HU |
Cusabio |
4280 mg |
Ask for price |
Recombinant Human Regulator of microtubule dynamics protein 3(RMDN3) |
AP71420 |
SAB |
1mg |
EUR 1978 |
|
Recombinant Human Conserved oligomeric Golgi complex subunit 5 (COG5), partial |
CSB-EP890771HU |
Cusabio |
8893 mg |
Ask for price |
RCAN1 Regulator of Calcineurin 1 Human Recombinant Protein |
PROTP53805 |
BosterBio |
Regular: 20ug |
EUR 380.4 |
Description: RCAN1 Isoform-b Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 117 amino acids and having a molecular mass of 13 kDa. |
RCAN2 Regulator of Calcineurin 2 Human Recombinant Protein |
PROTQ14206 |
BosterBio |
Regular: 20ug |
EUR 380.4 |
Description: RCAN2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 217 amino acids (1-197 a.a.) and having a molecular mass of 24.1kDa.;RCAN2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
Recombinant Human Active regulator of SIRT1 protein (RPS19BP1) |
CSB-RP006544h |
Cusabio |
5071 mg |
Ask for price |
Recombinant Human Active regulator of SIRT1 protein(RPS19BP1) |
AP71676 |
SAB |
1mg |
EUR 1978 |
|
Regulator of Calcineurin 3 Human Recombinant |
rAP-4634 |
Angio Proteomie |
Inquiry |
Ask for price |
RGS2 Regulator of G-Protein Signaling 2 Human Recombinant Protein |
PROTP41220 |
BosterBio |
Regular: 5ug |
EUR 380.4 |
Description: RGS2 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 231 amino acids (1-211a.a.) and having a molecular mass of 26.5 kDa. ;RGS2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
RGS4 Regulator of G-Protein Signaling 4 Human Recombinant Protein |
PROTP49798 |
BosterBio |
Regular: 10ug |
EUR 380.4 |
Description: RGS4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 225 amino acids (1-205 a.a.) and having a molecular mass of 25.4kDa.;RGS4 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
RGS1 Regulator of G-Protein Signaling 1 Human Recombinant Protein |
PROTQ08116 |
BosterBio |
Regular: 20ug |
EUR 380.4 |
Description: RGS1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 233 amino acids (1-209 a.a) and having a molecular mass of 26kDa.;RGS1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
RGS5 Regulator of G-Protein Signaling 5 Human Recombinant Protein |
PROTO15539 |
BosterBio |
Regular: 25ug |
EUR 380.4 |
Description: RGS5 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 205 amino acids (1-181 a.a.) and having a molecular mass of 23.5kDa.;RGS5 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
RGS19 Regulator of G-Protein Signaling 19 Human Recombinant Protein |
PROTP49795 |
BosterBio |
Regular: 20ug |
EUR 380.4 |
Description: RGS19 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 327 amino acids (1-217a.a.) and having a molecular mass of 26.7kDa.;RGS19 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
RGS17 Regulator of G-Protein Signaling 17 Human Recombinant Protein |
PROTQ9UGC6 |
BosterBio |
Regular: 25ug |
EUR 380.4 |
Description: RGS17 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 230 amino acids (1-210) and having a molecular mass of 26.5 kDa.;The RGS17 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. |
RGS21 Regulator of G-Protein Signaling 21 Human Recombinant Protein |
PROTQ2M5E4 |
BosterBio |
Regular: 20ug |
EUR 380.4 |
Description: RGS21 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 176 amino acids (1-152 a.a.) and having a molecular mass of 20.2kDa.;RGS21 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
RGS16 Regulator of G-Protein Signaling 16 Human Recombinant Protein |
PROTO15492 |
BosterBio |
Regular: 10ug |
EUR 380.4 |
Description: RGS16 Human Recombinant fused to 20 amino acid His Tag at N-terminal produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 222 amino acids (1-202 a.a.) and having a molecular mass of 24.9 kDa. _x000D_ The RGS16 is purified by proprietary chromatographic techniques._x000D_ |
RGS14 Regulator of G-Protein Signaling 14 Human Recombinant Protein |
PROTO43566 |
BosterBio |
Regular: 10ug |
EUR 380.4 |
Description: RGS14 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 586 amino acids (1-566 a.a) and having a molecular mass of 63.6kDa.;RGS14 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
RGS10 Regulator of G-Protein Signaling 10 Human Recombinant Protein |
PROTO43665 |
BosterBio |
Regular: 25ug |
EUR 380.4 |
Description: RGS10 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 205 amino acids (1-181) and having a molecular mass of 23.7 kDa.;The RGS10 is fused to a 24 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. |
OPCA00346-1MG - Recombinant human Active regulator of SIRT1 protein |
OPCA00346-1MG |
Aviva Systems Biology |
1mg |
EUR 1379 |
|
Recombinant Human Active regulator of SIRT1 Protein, GST, E.coli-1mg |
QP8330-ec-1mg |
EnQuireBio |
1mg |
EUR 1958.4 |
OPCA00346-100UG - Recombinant human Active regulator of SIRT1 protein |
OPCA00346-100UG |
Aviva Systems Biology |
100ug |
EUR 323 |
|
OPCA00346-20UG - Recombinant human Active regulator of SIRT1 protein |
OPCA00346-20UG |
Aviva Systems Biology |
20ug |
EUR 218 |
|
Recombinant Human Active regulator of SIRT1 Protein, GST, E.coli-10ug |
QP8330-ec-10ug |
EnQuireBio |
10ug |
EUR 240 |
Recombinant Human Active regulator of SIRT1 Protein, GST, E.coli-50ug |
QP8330-ec-50ug |
EnQuireBio |
50ug |
EUR 315.6 |
Recombinant Human Active regulator of SIRT1 Protein, GST, E.coli-100ug |
QP8330-ec-100ug |
EnQuireBio |
100ug |
EUR 489.6 |
Recombinant Human Active regulator of SIRT1 Protein, GST, E.coli-200ug |
QP8330-ec-200ug |
EnQuireBio |
200ug |
EUR 760.8 |
Recombinant Human Active regulator of SIRT1 Protein, GST, E.coli-500ug |
QP8330-ec-500ug |
EnQuireBio |
500ug |
EUR 1272 |
FUR Ferric Uptake Regulator E.Coli Recombinant Protein |
PROTP0A9A9 |
BosterBio |
Regular: 25ug |
EUR 380.4 |
Description: Ferric Uptake Regulator Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 148 amino acids and having a molecular mass of 16.7kDa. |
Recombinant Mouse Calmodulin regulator protein PCP4 (Pcp4) |
CSB-EP017636MO |
Cusabio |
7474 mg |
Ask for price |
Recombinant Human Regulator of G-protein signaling 10 Protein, GST, E.coli-1mg |
QP6602-ec-1mg |
EnQuireBio |
1mg |
EUR 1958.4 |
Recombinant Human Regulator of G-protein signaling 20 Protein, GST, E.coli-1mg |
QP6604-ec-1mg |
EnQuireBio |
1mg |
EUR 1958.4 |
Recombinant Human Regulator of G-protein signaling 7 Protein, His, E.coli-1mg |
QP6606-ec-1mg |
EnQuireBio |
1mg |
EUR 1958.4 |
Recombinant Human Regulator of G-protein signaling 10 Protein, GST, E.coli-100ug |
QP6602-ec-100ug |
EnQuireBio |
100ug |
EUR 489.6 |
Recombinant Human Regulator of G-protein signaling 10 Protein, GST, E.coli-10ug |
QP6602-ec-10ug |
EnQuireBio |
10ug |
EUR 240 |
Recombinant Human Regulator of G-protein signaling 10 Protein, GST, E.coli-200ug |
QP6602-ec-200ug |
EnQuireBio |
200ug |
EUR 760.8 |
Recombinant Human Regulator of G-protein signaling 10 Protein, GST, E.coli-500ug |
QP6602-ec-500ug |
EnQuireBio |
500ug |
EUR 1272 |
Recombinant Human Regulator of G-protein signaling 10 Protein, GST, E.coli-50ug |
QP6602-ec-50ug |
EnQuireBio |
50ug |
EUR 315.6 |
Recombinant Human Regulator of G-protein signaling 20 Protein, GST, E.coli-100ug |
QP6604-ec-100ug |
EnQuireBio |
100ug |
EUR 489.6 |
Recombinant Human Regulator of G-protein signaling 20 Protein, GST, E.coli-10ug |
QP6604-ec-10ug |
EnQuireBio |
10ug |
EUR 240 |
Recombinant Human Regulator of G-protein signaling 20 Protein, GST, E.coli-200ug |
QP6604-ec-200ug |
EnQuireBio |
200ug |
EUR 760.8 |
Recombinant Human Regulator of G-protein signaling 20 Protein, GST, E.coli-500ug |
QP6604-ec-500ug |
EnQuireBio |
500ug |
EUR 1272 |
Recombinant Human Regulator of G-protein signaling 20 Protein, GST, E.coli-50ug |
QP6604-ec-50ug |
EnQuireBio |
50ug |
EUR 315.6 |
Recombinant Human Regulator of G-protein signaling 7 Protein, His, E.coli-100ug |
QP6606-ec-100ug |
EnQuireBio |
100ug |
EUR 489.6 |
Recombinant Human Regulator of G-protein signaling 7 Protein, His, E.coli-10ug |
QP6606-ec-10ug |
EnQuireBio |
10ug |
EUR 240 |
Recombinant Human Regulator of G-protein signaling 7 Protein, His, E.coli-200ug |
QP6606-ec-200ug |
EnQuireBio |
200ug |
EUR 760.8 |
Recombinant Human Regulator of G-protein signaling 7 Protein, His, E.coli-500ug |
QP6606-ec-500ug |
EnQuireBio |
500ug |
EUR 1272 |
Recombinant Human Regulator of G-protein signaling 7 Protein, His, E.coli-50ug |
QP6606-ec-50ug |
EnQuireBio |
50ug |
EUR 315.6 |
Recombinant Human Regulator of microtubule dynamics protein 1, His, E.coli-1mg |
QP7878-ec-1mg |
EnQuireBio |
1mg |
EUR 1958.4 |
Recombinant human BMP-binding endothelial regulator protein |
P2637 |
FN Test |
100ug |
Ask for price |
|
Description: Recombinant protein for human BMP-binding endothelial regulator protein |
Recombinant Human Regulator of microtubule dynamics protein 1, His, E.coli-100ug |
QP7878-ec-100ug |
EnQuireBio |
100ug |
EUR 489.6 |
Recombinant Human Regulator of microtubule dynamics protein 1, His, E.coli-10ug |
QP7878-ec-10ug |
EnQuireBio |
10ug |
EUR 240 |
Recombinant Human Regulator of microtubule dynamics protein 1, His, E.coli-200ug |
QP7878-ec-200ug |
EnQuireBio |
200ug |
EUR 760.8 |
Recombinant Human Regulator of microtubule dynamics protein 1, His, E.coli-500ug |
QP7878-ec-500ug |
EnQuireBio |
500ug |
EUR 1272 |
Recombinant Human Regulator of microtubule dynamics protein 1, His, E.coli-50ug |
QP7878-ec-50ug |
EnQuireBio |
50ug |
EUR 315.6 |
Recombinant Human RGS5/ Regulator of G-protein signaling 5 Protein, GST, E.coli-1mg |
QP6605-ec-1mg |
EnQuireBio |
1mg |
EUR 1958.4 |
Recombinant Human Regulator of G-protein signaling 2 Protein, His-SUMO, E.coli-1mg |
QP6603-ec-1mg |
EnQuireBio |
1mg |
EUR 1958.4 |
Recombinant Human RGS5/ Regulator of G-protein signaling 5 Protein, GST, E.coli-100ug |
QP6605-ec-100ug |
EnQuireBio |
100ug |
EUR 489.6 |
Recombinant Human RGS5/ Regulator of G-protein signaling 5 Protein, GST, E.coli-10ug |
QP6605-ec-10ug |
EnQuireBio |
10ug |
EUR 240 |
Recombinant Human RGS5/ Regulator of G-protein signaling 5 Protein, GST, E.coli-200ug |
QP6605-ec-200ug |
EnQuireBio |
200ug |
EUR 760.8 |
Recombinant Human RGS5/ Regulator of G-protein signaling 5 Protein, GST, E.coli-500ug |
QP6605-ec-500ug |
EnQuireBio |
500ug |
EUR 1272 |
Recombinant Human RGS5/ Regulator of G-protein signaling 5 Protein, GST, E.coli-50ug |
QP6605-ec-50ug |
EnQuireBio |
50ug |
EUR 315.6 |
Prostate carcinoma (PC) is the second commonest most cancers in males. When the illness turns into unresponsive to androgen deprivation remedy, the remaining therapy choices are of restricted profit. Despite intense efforts, none of the T cell-based immunotherapeutic methods that in the meantime have turn into a cornerstone for therapy of different malignancies is established in PC. This refers to immune checkpoint inhibition (CI), which usually reinforces T cell immunity in addition to chimeric antigen receptor T (CAR-T) cells and bispecific antibodies (bsAbs) that stimulate the T cell receptor/CD3-complex and mobilize T cells in a focused method.
In normal, in comparison with CAR-T cells, bsAb would have the benefit of being an “off the shelf” reagent related to much less preparative effort, however at current, regardless of monumental efforts, neither CAR-T cells nor bsAbs are profitable in stable tumors. Here, we give attention to the varied bispecific constructs which are presently in growth for therapy of PC, and talk about underlying ideas and the state of medical analysis in addition to future views.