Steroid hormone

Steroid hormones are synthesized in the adrenal cortex, gonads, and placenta; all are derived from cholesterol and many are of clinical importance. Steroid hormones are synthesized in the mitochondria and the smooth endoplasmic reticulum. Because they are lipophilic, they cannot be stored in vesicles from which they would readily diffuse, and are therefore synthesized when needed as precursors. Upon stimulation of the stem cell, steroid hormone precursors are converted to active hormones and diffuse out of the stem cell by simple diffusion as their intracellular concentration increases.

Because all steroid hormones are derived from cholesterol, they are not soluble in plasma or other body fluids. As a result, the steroids bind to transport proteins that increase their half-life and ensure ubiquitous distribution. Protein-bound steroids are in equilibrium with a small fraction of free steroids, which are “active.” Steroids can act rapidly, by binding to cell surface receptors, or slowly, by binding to cytoplasmic or nucleic receptors, ultimately activating gene transcription.

The adrenal glands are made up of the adrenal medulla and the adrenal cortex. The adrenal cortex is divided into three main anatomic zones: the zona glomerulosa, which produces aldosterone; and the zona fasciculata and reticularis, which together produce cortisol and adrenal androgens. The medulla synthesizes catecholamines. More than 30 steroids are produced in the adrenal cortex; they can be divided into three functional categories: mineralocorticoids, glucocorticoids, and androgens. Steroids that are produced almost exclusively by the adrenal glands are cortisol, 11-deoxycortisol, aldosterone, corticosterone, and 11-deoxycorticosterone. Most other steroid hormones, including estrogens, are produced by the adrenal glands and gonads.

Mineralocorticoids

Mineralocorticoids are formed in the zona glomerulosa. The main function of mineralocorticoids is to promote tubular reabsorption of sodium and secretion of potassium and hydrogen ions in the collecting tubule, distal tubule, and collecting ducts. When sodium is reabsorbed, water is simultaneously absorbed. Sodium and water absorption increase fluid volume and blood pressure. Aldosterone is the most potent mineralocorticoid, accounting for about 90% of the total mineralocorticoid activity. Mineralocorticoid potency in descending order is aldosterone, 11-deoxycorticosterone, 18-oxocortisol, corticosterone, and cortisol.

Although cortisol has primarily glucocorticoid activity, it also has some mineralocorticoid activity. Cortisol has 1/400 the potency of aldosterone, but its concentration is about 80 times that of aldosterone. Adrenal production of cortisol is approximately 25 mg/day and that of aldosterone is 100 μg/day. Corticosterone has mainly glucocorticoid activity and some mineralocorticoid activity. Aldosterone secretion is regulated primarily by the renin-angiotensin system; it is also stimulated by increased serum potassium concentrations. Hyperkalemia and angiotensin II cause an increase in aldosterone. To a lesser extent, elevated sodium concentration suppresses aldosterone secretion, and corticotropin allows aldosterone secretion.

Glucocorticoids

Glucocorticoids are produced primarily in the zona fasciculata. Glucocorticoids affect metabolism in several ways. Glucocorticoids stimulate gluconeogenesis and decrease the use of glucose by cells. Cortisol reduces protein stores in all cells of the body except the liver and increases protein synthesis in the liver. Cortisol also increases amino acids in the blood, decreases amino acid transport to extrahepatic cells, and increases amino acid transport to liver cells. Cortisol mobilizes fatty acids from adipose tissue, increases plasma free fatty acids, and increases the use of free fatty acids for energy. Cortisol, the most clinically important glucocorticoid, accounts for approximately 95% of all glucocorticoid activity.

Corticosterone accounts for a small but significant amount of the total glucocorticoid activity. Cortisol secretion is regulated almost entirely by corticotropin, which is secreted by the anterior pituitary gland in response to corticotropin-releasing hormone (CRH) from the hypothalamus. Serum cortisol inhibits CRH and corticotropin secretion, thus preventing excessive cortisol secretion from the adrenal glands. Corticotropin stimulates cortisol secretion and promotes the growth of the adrenal cortex in conjunction with growth factors such as insulin-like growth factor (IGF)-1 and IGF-2. There is a circadian rhythm in cortisol secretion; the highest cortisol levels occur about 1 hour before waking up. Stress, pain, and inflammation cause increased cortisol production.

Androgens

The term “androgen” refers to any steroid hormone that has masculinizing effects. In men, androgens are responsible for the development of secondary sexual characteristics. Androgens play a less important role in women; however, adrenal androgens are responsible for much of the growth of pubic and axillary hair. Testosterone is the main androgen. Androgens are produced in the adrenal glands and the gonads. In men, the adrenal glands produce about 100 μg/day of testosterone and the testes produce about 7,000 μg/day. In women, 50% to 60% of testosterone is derived from androstenedione conversion in peripheral tissues, 30% is produced directly by the adrenal glands and 20% by the ovary.

Adrenal androgens are formed primarily in the zona reticularis. Dehydroepiandrosterone (DHEA) is the main steroid produced by the adrenal glands. The sulfation of DHEA produces DHEA sulfate (DHEA-S). Adrenal androgens are moderately active male sex hormones. Some of the adrenal androgens are converted to testosterone. The mechanism of stimulation of androgen secretion from the adrenal glands is not well understood. Adrenarche is the maturation of the adrenals, which causes an increase in these androgens and occurs between the ages of 5 and 20.

Adrenarche, therefore, begins well before puberty. Adrenal androgen secretion is partially regulated by corticotropin but also by other unknown factors. The testes secrete testosterone, dihydrotestosterone (DHT), and androstenedione. Gonadal androgen production is controlled by the hypothalamic secretion of GnRH, which causes the anterior pituitary to release follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Testosterone is secreted by the Leydig cells of the testes in response to LH stimulation. Most of the testosterone is converted to the more active DHT in target tissues.

Estrogens and progestins

In women, the main function of estrogen is to promote the proliferation and growth of specific cells in the body that is responsible for the development of most secondary sexual characteristics. Progestins are responsible for preparing the uterus for pregnancy and the breasts for lactation. In men, estrogens and progestins generally do not play a clinically significant role in the development of sexual characteristics. In women, estrogens and progestins are derived from the adrenal gland or the gonads. In women with intact ovaries, the adrenal contribution to circulating estrogen is negligible. Estrogens and progestins are secreted at different rates during different parts of the female menstrual cycle.

Estradiol is the prominent ovarian estrogen; estrone and estriol are two other estrogens. Estradiol is 12 times more potent than estrone and 80 times more potent than estriol. The ovaries produce estrone in small amounts, but most of it is formed by peripheral conversion from androgens. Estriol is primarily a metabolite of estrone and estradiol in non-pregnant women. In pregnancy, however, estriol is the main placental estrogen. DHEA-S from the fetal adrenal glands is converted to estriol by the placenta.

The main progestin is progesterone; a minor progestin is 17-hydroxy-progesterone. In the first half of the menstrual cycle, small amounts of progesterone are produced, about half by the ovaries and half by the adrenal cortex. Larger amounts of progesterone are secreted in the last half of the menstrual cycle by the corpus luteum. Men produce a small amount of estrogen (about 1/5 of the production of a non-pregnant woman). Sertoli cells convert a small amount of testosterone to estrogen. Also, estrogens are formed from testosterone and androstenediol in the periphery of the liver.

Animals

Discover different types of animals today

A-Z Animals is the world’s most trusted online animal encyclopedia. Whether you want cute animals, types of wild animals, exotic pets, strange animals, or are looking for complete pet guides for dogs and cats, you’ll find it here! We believe that if people know more about the world’s creatures, they will take better care of them. That’s why we add new animals for you to discover, every day!

The 7 main different types of animals

1. Mammals

The official class of mammals is Mammalia. Animals that are considered mammals include warm-blooded vertebrates that have hair or fur and whose young drink milk. Unlike other types of animals such as birds and insects, all mammalian babies drink milk that comes from their mother’s body. This is one of the key ways to tell if an animal is a mammal.

2. Reptiles

Lizards, dinosaurs, crocodiles, turtles, and snakes all belong to that ancient and robust class of animals known as reptiles. This is a diverse group with more than 10,000 different species and a large representation in the fossil record. Once the dominant terrestrial vertebrates on the planet, reptiles still occupy nearly every ecosystem outside of the far north and south.

Animals - Facts, Pictures and Resources - AZ Animals

3. Fish

Fish are aquatic vertebrates. They typically have gills, paired fins, a long, scale-covered body, and tend to be cold-blooded. “Fishes” is a term used to refer to lampreys, sharks, coelacanths, and ray-finned fishes, but it is not a taxonomic group, which is a clade or group containing a common ancestor and all its descendants.

4. Birds

Birds, members of the class Aves, include more than 10,400 living species. Their feathers distinguish them from all other classes of animals; no other animal on earth has them. If you see an animal with feathers, it is definitely a bird. Like mammals, birds are warm-blooded vertebrates with four-chambered hearts. However, they are more closely related to reptiles and are thought to have evolved from dinosaurs.

5. Amphibians

The official class of amphibians is Amphibia. To qualify as an amphibian, an animal must be a vertebrate, require water to survive, be cold-blooded, and spend time both on land and in water. Although other animals only live on land or in water, amphibians have the unique ability to thrive equally in both. Amphibians cover more than 6,000 different species worldwide, but around 90% of them are frogs.

6. Invertebrates

The definition of an invertebrate is any animal that does not have a backbone or backbone. The most prolific and easily recognizable members of the invertebrate family are insects. It is estimated that there may be more than 30 million individual species of invertebrates that represent between 90 and 95 per cent of all organisms on the planet.

7. Insects

All insects are part of the taxonomic phylum Arthropoda and are collectively known as arthropods. It is common to see this name misspelt as “anthropoid”, but this is not the correct term. They can be found in almost every environment on the planet and currently account for more than half of all known living organisms in the world. They have gone through many cycles of evolution depending on the resources available to them.

Vaccine

Vaccine, suspension of weakened, killed, or fragmented microorganisms or toxins, or other biological preparation, such as those consisting of antibodies, lymphocytes, or messenger RNA (mRNA), that is given primarily to prevent disease. A vaccine can confer active immunity against a specific harmful agent by stimulating the immune system to attack the agent. Once stimulated by a vaccine, antibody-producing cells called B cells (or B lymphocytes) remain sensitized and ready to respond to the agent should it ever enter the body.

A vaccine can also confer passive immunity by providing antibodies or lymphocytes already produced by an animal or human donor. Vaccines are usually given by injection (parenteral administration), but some are given orally or even through the nose (in the case of the flu vaccine). Vaccines applied to mucosal surfaces, such as those lining the gut or nasal passages, appear to stimulate a greater antibody response and maybe the most effective route of administration.

The first vaccinations

The first vaccine was introduced by British physician Edward Jenner, who in 1796 used the cowpox virus (vaccinia) to confer protection against smallpox, a related virus, in humans. However, before such use, Asian doctors applied the principle of vaccination and gave children dried scabs from the lesions of people suffering from smallpox to protect against the disease.

While some developed immunity, others developed the disease. Jenner’s contribution was to use a substance similar to, but safer than, smallpox to confer immunity. Thus, he took advantage of the relatively rare situation in which immunity to one virus confers protection against another viral disease. In 1881, French microbiologist Louis Pasteur demonstrated immunization against anthrax by injecting sheep with a preparation containing attenuated forms of the bacillus that causes the disease. Four years later he developed a protective suspension against rabies.

Vaccine effectiveness

After the time of Pasteur, an intensive and widespread search for new vaccines was carried out, and vaccines against bacteria and viruses, as well as vaccines against poisons and other toxins, were produced. Through vaccination, smallpox was eradicated worldwide in 1980 and polio cases were reduced by 99 per cent. Other examples of diseases for which vaccines have been developed include mumps, measles, typhoid, cholera, plague, tuberculosis, tularemia, pneumococcal infection, tetanus, influenza, yellow fever, hepatitis A, hepatitis B, some types of encephalitis, and typhus. although some of those vaccines are less than 100 per cent effective or are used only in high-risk populations. Vaccines against viruses provide particularly important immune protection because, unlike bacterial infections, viral infections do not respond to antibiotics.

Types of vaccines

The challenge in vaccine development is to design a vaccine strong enough to prevent infection without making the individual seriously ill. To that end, researchers have devised different types of vaccines. Weakened or attenuated vaccines consist of microorganisms that have lost the ability to cause serious disease but retain the ability to stimulate immunity. They can produce a mild or subclinical form of the disease. Attenuated vaccines include measles, mumps, polio (the Sabin vaccine), rubella, and tuberculosis. Inactivated vaccines are those that contain organisms that have been killed or inactivated with heat or chemicals.

Inactivated vaccines elicit an immune response, but the response is usually less complete than with live vaccines. Because inactivated vaccines are not as effective in fighting infections as those made with attenuated microorganisms, larger quantities of inactivated vaccines are administered. Vaccines against rabies, polio (the Salk vaccine), some forms of influenza, and cholera are made from inactivated microorganisms. Another type of vaccine is a subunit vaccine, which is made from proteins found on the surface of infectious agents. Influenza and hepatitis B vaccines are of that type. When toxins, the metabolic byproducts of infectious organisms, are inactivated to form toxoids, they can be used to boost immunity against tetanus, diphtheria, and whooping cough (whooping cough).

In the late 20th century, advances in laboratory techniques allowed for the refinement of approaches to vaccine development. Medical researchers could identify the genes of a pathogen (disease-causing microorganism) that code for the protein or proteins that stimulate the immune response to that organism. That allowed immune-stimulating proteins (called antigens) to be mass-produced and used in vaccines. It also made it possible to genetically alter pathogens and produce weakened strains of viruses. In this way, the harmful proteins of pathogens can be removed or modified, thus providing a safer and more effective method of manufacturing attenuated vaccines.

Recombinant DNA technology has also proven useful in developing vaccines against viruses that cannot be cultured successfully or are inherently dangerous. The genetic material that codes for the desired antigen is inserted into the attenuated form of a large virus, such as the vaccinia virus, which “piggybacks” the foreign genes. The altered virus is injected into an individual to stimulate the production of antibodies against foreign proteins and thus confer immunity. The approach potentially allows the vaccinia virus to function as a live vaccine against various diseases, once it has received genes derived from the relevant disease-causing microorganisms.

A similar procedure can be followed using a modified bacterium, such as Salmonella typhimurium, as the carrier of a foreign gene. Human papillomavirus (HPV) vaccines are made from virus-like particles (VLPs), which are prepared using recombinant technology. The vaccines do not contain live biological or genetic material from HPV and therefore cannot cause infection. Two types of HPV vaccines have been developed, including a bivalent HPV vaccine, made with VLPs of HPV types 16 and 18, and a quadrivalent vaccine, made with VLPs of HPV types 6, 11, 16 and 18.

Induction of Cross-reactive Hemagglutination Inhibiting Antibody and Polyfunctional CD4+ T-cell Responses by a Recombinant Matrix-M-Adjuvanted Hemagglutinin Nanoparticle Influenza Vaccine

Identification and characterization of CD4+ T cell epitopes after Shingrix vaccination
Recurrent experiences of suboptimal influenza vaccine effectiveness have renewed calls to develop improved, broadly cross-protective influenza vaccines. Here, we evaluated the protection and immunogenicity of a novel, saponin (Matrix-M)-adjuvanted, recombinant hemagglutinin (HA) quadrivalent nanoparticle influenza vaccine (qNIV). We carried out a randomized, observer-blind, comparator-controlled (trivalent high-dose inactivated influenza vaccine [IIV3-HD]
or quadrivalent recombinant influenza vaccine [RIV4]), security and immunogenicity trial of qNIV (in 5 completely different doses/formulations) in wholesome adults aged ≥65 years. Vaccine immunogenicity was measured by hemagglutination-inhibition assays utilizing reagents expressing wild-type HA sequences (wt-HAI) and cell-mediated immune (CMI) responses. Only lately, nonetheless, have NHP MAIT cells been completely characterised utilizing macaque-specific MR1 tetramer reagents. Here we overview the similarities and variations between MAIT cells in people and NHPs in addition to the influence of SIV/SHIV an infection on MAIT cells and the potential implications for future analysis.
A complete of 1375 contributors had been randomized, immunized, and adopted for security and immunogenicity. Matrix-M-adjuvanted qNIV induced superior wt-HAI antibody responses towards 5 of 6 homologous or drifted strains evaluated in comparison with unadjuvanted qNIV. Adjuvanted qNIV induced post-vaccination wt-HAI antibody responses at Day 28 that had been: statistically greater than IIV3-HD towards a panel of homologous or drifted A/H3N2 strains; just like IIV3-HD towards homologous A/H1N1 and B (Victoria) strains; and just like RIV4 towards all homologous and drifted strains evaluated. The qNIV formulation with 75 µg Matrix-M adjuvant induced considerably greater post-vaccination geometric imply fold-increases of influenza HA-specific polyfunctional CD4+ T-cells in comparison with IIV3-HD or RIV4. Overall, related frequencies of solicited and unsolicited hostile occasions (AEs) had been reported in all therapy group

The N-terminal cysteine protease area of rice stripe tenuivirus Pc1 possesses deubiquitinating enzyme exercise

Virus encoded deubiquitinating enzyme (DUB) performs necessary roles in viral replication and the regulation of host innate immunity. Bioinformatics-based evaluation revealed the presence of an ovarian tumor (OTU) protease area within the N terminus of rice stripe tenuivirus (RSV) Pc1. Many viral OTU domains have been reported to own DUB exercise, which means that RSV OTU in all probability even have DUB exercise. To affirm this prediction, we first expressed and purified RSV OTU area (the N-terminal 200 amino acids of Pc1) and its three mutants (D42A, C45A and H148A) from Escherichia coli and analyzed its DUB exercise in vitro.

 

The purified RSV OTU hydrolyzed each Ok48-linked and Ok63-linked polyubiquitin chains, indicating RSV OTU area has DUB enzyme exercise in vitro. The mutations of the expected catalytic websites (Asp42, Cys45 and His148) resulted within the loss of DUB exercise, demonstrating these three residues had been required for enzyme exercise. Then, RSV OTU and its mutants had been expressed in insect cells and assayed their DUB actions in vivo by co-transfection with HA-tagged ubiquitin. RSV OTU dramatically lowered ubiquitin-conjugated mobile proteins in comparison with management and the mutants, exhibiting that RSV OTU additionally shows DUB exercise in vivo.

Characterization of RSV OTU DUB enzyme exercise and its key catalytic residues will facilitate the event of novel antiviral reagents towards RSV.Chronic HIV an infection causes systemic immune activation and dysregulation, ensuing within the impairment of most T-cell subsets together with MAIT cells. Multiple human cohort research display MAIT cells are selectively depleted within the peripheral blood and lymphoid tissues throughout HIV an infection, with incomplete restoration throughout suppressive antiretroviral remedy.

Because MAIT cells play an necessary function in mucosal protection towards a big range of pathogens, absolutely reconstituting the MAIT cell compartment in ART-treated populations may enhance immunity towards co-infections. Non-human primates (NHPs) are a useful, well-described animal mannequin for HIV an infection in people. NHPs additionally preserve MAIT cell frequencies extra corresponding to people, in comparison with different frequent animal fashions, and present a distinctive alternative to check MAIT cells within the circulation and mucosal tissues in a longitudinal method.

Induction of Cross-reactive Hemagglutination Inhibiting Antibody and Polyfunctional CD4+ T-cell Responses by a Recombinant Matrix-M-Adjuvanted Hemagglutinin Nanoparticle Influenza Vaccine

Serum Health Biomarkers in African and Asian Elephants: Value Ranges and Clinical Values Indicative of the Immune Response

Serum biomarkers indicative of irritation and illness can present helpful data concerning host immune processes, responses to therapy and prognosis. The goals of this research had been to evaluate the use of commercially accessible anti-equine reagents for the quantification of cytokines (tumor necrosis factor-alpha (TNF-α), interferon-gamma (IFN-γ), interleukins (IL) 2, 6, and 10) in African (Loxodonta africana, n = 125) and Asian (Elephas maximus, n = 104) elephants, and alongside beforehand validated anti-human reagents for acute-phase proteins (serum amyloid A and haptoglobin), calculate species-specific biomarker worth ranges. In addition, we used opportunistically collected samples to analyze the concentrations of every biomarker throughout recognized scientific circumstances of sickness or damage, as a first step to understanding what biomarkers could also be helpful to managing elephant well being.

Immunity-Related GTPase Family Q Protein (IRGQ) Antibody

abx032348-400ul 400 ul
EUR 551

Immunity-Related GTPase Family Q Protein (IRGQ) Antibody

abx032348-80l 80 µl
EUR 321

Immunity-Related GTPase Family M Protein (IRGM) Protein

20-abx260986
  • EUR 3418.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug

Immunity-Related GTPase Family Q Protein (IRGQ) Antibody

abx234399-100ug 100 ug
EUR 551

Immunity-Related GTPase Family M Protein (IRGM) Antibody

20-abx210849
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Immunity-Related GTPase Family M Protein (IRGM) Antibody

abx448534-100ug 100 ug
EUR 523

IRGM Immunity-Related GTPase Family, M Human Recombinant Protein

PROTA1A4Y4 Regular: 20ug
EUR 317
Description: IRGM Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 180 amino acids (23-181) and having a molecular mass of 20.1 kDa. IRGM is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ALP)

abx448005-100ug 100 ug
EUR 578

Immunity-Related GTPase Family M Protein (IRGM) Antibody (APC)

abx448006-100ug 100 ug
EUR 578

Immunity-Related GTPase Family M Protein (IRGM) Antibody (Biotin)

abx448007-100ug 100 ug
EUR 578

Immunity-Related GTPase Family M Protein (IRGM) Antibody (FITC)

abx448008-100ug 100 ug
EUR 565

Immunity-Related GTPase Family M Protein (IRGM) Antibody (HRP)

abx448009-100ug 100 ug
EUR 565

Immunity-Related GTPase Family M Protein (IRGM) Antibody (PerCP)

abx448011-100ug 100 ug
EUR 578

Immunity-Related GTPase Family M Protein (IRGM) Antibody (RPE)

abx448012-100ug 100 ug
EUR 578

Immunity-Related GTPase Family M Protein (IRGM) Antibody (Streptavidin)

abx448013-100ug 100 ug
EUR 578

Immunity Related GTPase M (IRGM) Antibody

abx412110-01mg 0.1 mg
EUR 537

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO 390)

abx447997-100ug 100 ug
EUR 578

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO 488)

abx447998-100ug 100 ug
EUR 578

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO 565)

abx447999-100ug 100 ug
EUR 578

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO 594)

abx448000-100ug 100 ug
EUR 578

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO 633)

abx448001-100ug 100 ug
EUR 578

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO 655)

abx448002-100ug 100 ug
EUR 578

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO 680)

abx448003-100ug 100 ug
EUR 578

Immunity-Related GTPase Family M Protein (IRGM) Antibody (ATTO 700)

abx448004-100ug 100 ug
EUR 578

Human Immunity-Related GTPase Family Q Protein (IRGQ) ELISA Kit

abx388031-96tests 96 tests
EUR 911

Human Immunity- related GTPase family M protein, IRGM ELISA KIT

ELI-48787h 96 Tests
EUR 824

Mouse Immunity- related GTPase family Q protein, Irgq ELISA KIT

ELI-48788m 96 Tests
EUR 865

Rat Immunity- related GTPase family M protein, Irgm ELISA KIT

ELI-20422r 96 Tests
EUR 886

Human Immunity- related GTPase family Q protein, IRGQ ELISA KIT

ELI-13087h 96 Tests
EUR 824

Immunity-Related GTPase Family M Protein (IRGM) Antibody (PE/ATTO 594)

abx448010-100ug 100 ug
EUR 592

Mouse Immunity- related GTPase family M protein 1, Irgm1 ELISA K

ELI-43703m 96 Tests
EUR 865

Recombinant Human Immunity-related GTPase family M protein Protein, GST, E.coli-100ug

QP6236-ec-100ug 100ug
EUR 408

Recombinant Human Immunity-related GTPase family M protein Protein, GST, E.coli-10ug

QP6236-ec-10ug 10ug
EUR 200

Recombinant Human Immunity-related GTPase family M protein Protein, GST, E.coli-1mg

QP6236-ec-1mg 1mg
EUR 1632

Recombinant Human Immunity-related GTPase family M protein Protein, GST, E.coli-200ug

QP6236-ec-200ug 200ug
EUR 634

Recombinant Human Immunity-related GTPase family M protein Protein, GST, E.coli-500ug

QP6236-ec-500ug 500ug
EUR 1060

Recombinant Human Immunity-related GTPase family M protein Protein, GST, E.coli-50ug

QP6236-ec-50ug 50ug
EUR 263

Recombinant Rho Family GTPase 1 (RND1)

4-RPB788Hu01
  • EUR 377.76
  • EUR 204.00
  • EUR 1141.60
  • EUR 447.20
  • EUR 794.40
  • EUR 316.00
  • EUR 2704.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Rho Family GTPase 1 expressed in: E.coli

Rho Family GTPase 1 (RND1) Antibody

20-abx130669
  • EUR 411.00
  • EUR 133.00
  • EUR 1149.00
  • EUR 565.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rho Family Gtpase 2 (RND2) Antibody

20-abx115176
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Rho Family Gtpase 3 (RND3) Antibody

20-abx115177
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Rho Family GTPase 2 (RND2) Antibody

20-abx121211
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

DIRAS Family GTPase 3 (DIRAS3) Antibody

20-abx112094
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

DIRAS Family GTPase 3 (DIRAS3) Antibody

20-abx320343
  • EUR 300.00
  • EUR 244.00
  • 100 ul
  • 50 ul

Rho Family GTPase 2 (RND2) Antibody

20-abx318052
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

DIRAS Family GTPase 3 (DIRAS3) Antibody

20-abx339162
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Recombinant Human Rho Family GTPase 1

7-06157 5µg Ask for price

Recombinant Human Rho Family GTPase 1

7-06158 20µg Ask for price

Recombinant Human Rho Family GTPase 1

7-06159 1mg Ask for price

Recombinant Human Rho Family GTPase 3

7-06160 5µg Ask for price

Recombinant Human Rho Family GTPase 3

7-06161 20µg Ask for price

Recombinant Human Rho Family GTPase 3

7-06162 1mg Ask for price

Rho Family GTPase 1 (RND1) Antibody

abx145149-100ug 100 ug
EUR 391

DIRAS Family GTPase 3 (DIRAS3) Antibody

20-abx006587
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

DIRAS Family GTPase 3 (DIRAS3) Antibody

abx032656-400ul 400 ul
EUR 523

DIRAS Family GTPase 3 (DIRAS3) Antibody

abx032656-80l 80 µl
EUR 286

GTPase, IMAP Family Member 6 Protein

20-abx261940
  • EUR 4490.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 20 ug
  • 5 ug

GTPase, IMAP Family Member 5 Protein

20-abx262699
  • EUR 328.00
  • EUR 6397.00
  • EUR 230.00
  • 10 ug
  • 1 mg
  • 2 µg

Rho Family GTPase 2 (RND2) Antibody

abx237332-100ug 100 ug
EUR 509

Rho Family GTPase 2 (RND2) Antibody

20-abx218322
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug

DIRAS Family GTPase 3 (DIRAS3) Antibody

20-abx225145
  • EUR 370.00
  • EUR 606.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 50 ul

GTPase IMAP Family Member 2 (GIMAP2) Antibody

20-abx112878
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

GTPase IMAP Family Member 4 (GIMAP4) Antibody

20-abx112879
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

GTPase IMAP Family Member 5 (GIMAP5) Antibody

20-abx112880
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

GTPase IMAP Family Member 7 (GIMAP7) Antibody

20-abx112881
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

GTPase IMAP Family Member 5 (GIMAP5) Antibody

20-abx124690
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Rho Family GTPase 2 (RND2) Antibody (HRP)

20-abx315972
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Rho Family GTPase 2 (RND2) Antibody (FITC)

20-abx315973
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Rho Family GTPase 2 (RND2) Antibody (Biotin)

20-abx315974
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

GTPase IMAP Family Member 4 (GIMAP4) Antibody

abx146087-100ug 100 ug
EUR 391

GTPase IMAP Family Member 4 (GIMAP4) Antibody

20-abx008113
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

GTPase IMAP Family Member 8 (GIMAP8) Antibody

abx027293-400ul 400 ul
EUR 523

GTPase IMAP Family Member 8 (GIMAP8) Antibody

abx027293-80l 80 µl
EUR 286

GTPase IMAP Family Member 2 (GIMAP2) Antibody

20-abx014508
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

GTPase IMAP Family Member 4 (GIMAP4) Antibody

20-abx014509
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

GTPase IMAP Family Member 5 (GIMAP5) Antibody

20-abx014510
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

GTPase IMAP Family Member 2 (GIMAP2) Antibody

abx233456-100ug 100 ug
EUR 551

GTPase IMAP Family Member 4 (GIMAP4) Antibody

abx233457-100ug 100 ug
EUR 551

GTPase IMAP Family Member 5 (GIMAP5) Antibody

abx233458-100ug 100 ug
EUR 551

GTPase IMAP Family Member 7 (GIMAP7) Antibody

abx233459-100ug 100 ug
EUR 551

Human Rho Family GTPase 1 (RND1) Protein

20-abx168764
  • EUR 537.00
  • EUR 244.00
  • EUR 1553.00
  • EUR 634.00
  • EUR 398.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

GTPase IMAP Family Member 7 (GIMAP7) Antibody

20-abx302667
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

GTPase IMAP Family Member 7 (GIMAP7) Antibody

20-abx216118
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug

GTPase IMAP Family Member 2 (GIMAP2) Antibody

abx330512-100ul 100 ul
EUR 425

GTPase IMAP Family Member 5 (GIMAP5) Antibody

abx330629-100ul 100 ul
EUR 425

GTPase IMAP Family Member 4 (GIMAP4) Antibody

abx330973-100ul 100 ul
EUR 425

GTPase IMAP Family Member 2 (GIMAP2) Antibody

20-abx324240
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

GTPase IMAP Family Member 5 (GIMAP5) Antibody

20-abx324499
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

GTPase IMAP Family Member 4 (GIMAP4) Antibody

20-abx324751
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Recombinant human GTPase IMAP family member 1

P2329 100ug Ask for price
Description: Recombinant protein for human GTPase IMAP family member 1

Human Rho family GTPase 1 ELISA Kit

ELA-E1788h 96 Tests
EUR 824

Human Tumor Immunity Primer Library

HTIMU-I 1 set
EUR 548

Mouse Tumor Immunity Primer Library

MTIMU-I 1 set
EUR 548

Secretion Associated Ras Related GTPase 1A (SAR1A) Antibody

20-abx322470
  • EUR 439.00
  • EUR 328.00
  • 100 ul
  • 50 ul

Secretion Associated Ras Related GTPase 1B (SAR1B) Antibody

20-abx003558
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul

Secretion Associated Ras Related GTPase 1B (SAR1B) Antibody

20-abx133516
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

Secretion Associated Ras Related GTPase 1A (SAR1A) Antibody

20-abx006980
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Secretion Associated Ras Related GTPase 1B (SAR1B) Antibody

abx025703-400ul 400 ul
EUR 523

Secretion Associated Ras Related GTPase 1B (SAR1B) Antibody

abx025703-80l 80 µl
EUR 286

Secretion Associated Ras Related GTPase 1A (SAR1A) Antibody

abx033062-400ul 400 ul
EUR 523

Secretion Associated Ras Related GTPase 1A (SAR1A) Antibody

abx033062-80l 80 µl
EUR 286

Secretion Associated Ras Related GTPase 1B (SAR1B) Antibody

20-abx014515
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Secretion Associated Ras Related GTPase 1B (SAR1B) Antibody

abx430444-200ul 200 ul
EUR 384

Secretion Associated Ras Related GTPase 1A (SAR1A) Antibody

abx237601-100ug 100 ug
EUR 509

Secretion Associated Ras Related GTPase 1A (SAR1A) Antibody

abx237602-100ug 100 ug
EUR 509

Secretion Associated Ras Related GTPase 1B (SAR1B) Antibody

abx237603-100ug 100 ug
EUR 509

Secretion Associated Ras Related GTPase 1B (SAR1B) Antibody

abx237604-100ug 100 ug
EUR 509

Secretion Associated Ras Related GTPase 1B (SAR1B) Antibody

20-abx213797
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Secretion Associated Ras Related GTPase 1B (SAR1B) Antibody

20-abx213798
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Secretion Associated Ras Related GTPase 1A (SAR1A) Antibody

20-abx218438
  • EUR 425.00
  • EUR 342.00
  • 100 ug
  • 50 ug

Secretion Associated Ras Related GTPase 1B (SAR1B) Antibody

abx332487-100ul 100 ul
EUR 425

Secretion Associated Ras Related GTPase 1B (SAR1B) Antibody

20-abx328673
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Rho Family GTPase 1 (RND1) Polyclonal Antibody (Human)

4-PAB788Hu01
  • EUR 239.00
  • EUR 2391.00
  • EUR 598.00
  • EUR 299.00
  • EUR 211.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Rho Family GTPase 1 (RND1)

RND3 Rho Family GTPase 3 Human Recombinant Protein

PROTP61587 Regular: 20ug
EUR 317
Description: RND3 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 261 amino acids (1-241 a.a.) and having a molecular mass of 29.2 kDa. The RND3 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.

RND1 Rho Family GTPase 1 Human Recombinant Protein

PROTQ92730 Regular: 20ug
EUR 317
Description: RND1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 220 amino acids (1-200) and having a molecular mass of 24.5 kDa.;The RND1 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.

Human Rho family GTPase 1(RND1)ELISA Kit

GA-E0835HM-48T 48T
EUR 289

Human Rho family GTPase 1(RND1)ELISA Kit

GA-E0835HM-96T 96T
EUR 466

human Rho family GTPase 1,RND1 ELISA Kit

201-12-0819 96 tests
EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

GTPase IMAP Family Member 7 (GIMAP7) Antibody (HRP)

20-abx308780
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

GTPase IMAP Family Member 7 (GIMAP7) Antibody (FITC)

20-abx308781
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

GTPase IMAP Family Member 7 (GIMAP7) Antibody (Biotin)

20-abx308782
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Sheep Rho Family GTPase 1 (RND1) ELISA Kit

abx364427-96tests 96 tests
EUR 926

Human Rho Family GTPase 2 (RND2) ELISA Kit

abx382837-96tests 96 tests
EUR 911

Human Rho Family GTPase 3 (RND3) ELISA Kit

abx382838-96tests 96 tests
EUR 911

Pig Rho Family GTPase 1 (RND1) ELISA Kit

abx361462-96tests 96 tests
EUR 825

Rabbit Rho Family GTPase 1 (RND1) ELISA Kit

abx362433-96tests 96 tests
EUR 825

Human Rho Family GTPase 1 (RND1) ELISA Kit

abx354483-96tests 96 tests
EUR 786

Chicken Rho Family GTPase 1 (RND1) ELISA Kit

abx356387-96tests 96 tests
EUR 825

Monkey Rho Family GTPase 1 (RND1) ELISA Kit

abx359680-96tests 96 tests
EUR 825

Human Rho family GTPase 1(RND1)ELISA Kit

QY-E04647 96T
EUR 394

Recombinant human Innate immunity activator protein

P1297 100ug Ask for price
Description: Recombinant protein for human Innate immunity activator protein

Rho Family GTPase 1 (RND1) Polyclonal Antibody (Human), APC

4-PAB788Hu01-APC
  • EUR 333.00
  • EUR 3113.00
  • EUR 872.00
  • EUR 423.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Rho Family GTPase 1 (RND1). This antibody is labeled with APC.

Rho Family GTPase 1 (RND1) Polyclonal Antibody (Human), Biotinylated

4-PAB788Hu01-Biotin
  • EUR 303.00
  • EUR 2341.00
  • EUR 697.00
  • EUR 369.00
  • EUR 216.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Rho Family GTPase 1 (RND1). This antibody is labeled with Biotin.

Rho Family GTPase 1 (RND1) Polyclonal Antibody (Human), Cy3

4-PAB788Hu01-Cy3
  • EUR 403.00
  • EUR 4109.00
  • EUR 1121.00
  • EUR 523.00
  • EUR 245.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Rho Family GTPase 1 (RND1). This antibody is labeled with Cy3.

Rho Family GTPase 1 (RND1) Polyclonal Antibody (Human), FITC

4-PAB788Hu01-FITC
  • EUR 287.00
  • EUR 2510.00
  • EUR 717.00