CD4+T cell epitopes performs a key position in anti-tuberculosis (TB) immunity, CD4+T cell epitopes appropriate for the home inhabitants are missing. Therefore, we predicted and recognized novel CD4+T cell epitopes.The bioinformatics software program, specifically, DNAStar (DNASTAR of the United States), SYFPEITHI (INTERFACTORS INSTITUT Für ZELL Biologie of Germany), RANKPEP, and NetMHC IIpan (National Cancer Institute, United States of America), have been used to comprehensively predict the CD4+T cell immune epitope of Mycobacterium TB, and the predicted epitope polypeptide was synthesized by the commonplace Fmoc scheme. The proliferation of PBMC and CD4+T cells stimulated by peptides was preliminarily detected by the CCK8 technique.
Then, the candidate polypeptides screened out by the CCK8 technique have been verified once more by the BrdU assay, and movement cytometry was carried out to investigate additional the extent of their stimulation on the proliferation of CD4+T cells. The adjustments in the secreted cytokines IFN-γ, TNF-α, IL-2, and IL-10 earlier than and after the candidate polypeptide stimulation of CD4+T lymphocytes have been detected by ELISA. The preliminary humoral immunity take a look at was carried out by oblique ELISA to judge the serological diagnostic worth of the CD4+T cell epitope polypeptide.
In this research, 5 novel candidate CD4+T cell epitope polypeptides with the amino acid sequences of LQGQWRGAAGTAAQA, PVTLAETGSTLLYPL, AAAWGGSGSEAYQGV, QFVYAGAMSGLLDPS, and KAALTRTASNMNAAA and others that haven’t been reported in the analysis have been predicted. For comfort, the 5 candidates have been successively named as P39, P50, P40, P185, and P62. P39, P62, and the blended peptide P39+P62 may successfully induce the proliferation of CD4+T cells and improve the secretion of IFN-γ, TNF-α, and IL-2 from the CD4+T cells, whereas lowering the content material of IL-10.
The serological take a look at confirmed that the sensitivity, specificity, and space below the receiver working attribute curve (AUC) of P39 have been 75%, 67.71%, and 0.844, respectively. The sensitivity, specificity, and AUC of P62 have been 91.66%, 46.87%, and 0.649, respectively. The sensitivity of the blended peptide P39+P62 was 95.83%, the specificity was 97.91%, and the AUC was 0.793.The P39 and P62 polypeptides have been predicted and recognized as potential CD4+T cell immune epitope polypeptides of M. TB. The polypeptide had higher analysis impact, which offered potential candidate epitope polypeptides for the growth of TB-specific analysis reagents and novel TB epitope vaccines.
Dietary Chitosan Nanoparticles: Potential Role in Modulation of Rainbow Trout ( Oncorhynchus mykiss) Antibacterial Defense and Intestinal Immunity in opposition to Enteric Redmouth Disease
Bio-nanotechnology using bio-sourced nanomaterial is an rising avenue serving the area of fish drugs. Marine-sourced chitosan nanoparticles (CSNPs) is a widely known antimicrobial and immunomodulatory reagent with low or no hurt uncomfortable side effects on fish or their human customers. In this research, in vitro pores and skin mucus and serum antibacterial exercise assays together with intestinal histology, histochemical, and gene expression analyses have been carried out to judge the impression of dietary CSNPs (5 g kg-1 dry feed) on rainbow trout resistance in opposition to ‘enteric redmouth’ illness. Two therapy situations have been included; short-term prophylactic-regimen for 21 days earlier than the bacterial problem, and long-term therapeutic-regimen for 21 days earlier than the problem and prolonged for 28 days after the problem.
Our outcomes revealed larger antibacterial protection means and optimistic intestinal histochemical and molecular traits of rainbow trout after dietary CSNPs. The prophylactic-regimen improved trout well being whereas the therapeutic routine improved their illness resistance and lowered their morbidity. Therefore, it’s anticipated that CSNPs is an efficient antibacterial and immunomodulatory fish feed complement in opposition to the infectious threats. However, the CSNPs appear to be simpler in the therapeutic utility relatively than getting used for short-term prophylactic purposes.
The Koala Immune Response to Chlamydial Infection and Vaccine Development-Advancing Our Immunological Understanding
Chlamydia is a major pathogen for many species, together with the much-loved Australian marsupial, the koala (Phascolarctos cinereus). To fight this case, centered analysis has gone into the growth and refinement of a chlamydial vaccine for koalas. The basis of this course of has concerned characterising the immune response of koalas to each pure chlamydial an infection in addition to vaccination. From parallels in human and mouse analysis, it’s well-established that an efficient anti-chlamydial response will contain a stability of cell-mediated Th1 responses involving interferon-gamma (IFN-γ), humoral Th2 responses involving systemic IgG and mucosal IgA, and inflammatory Th17 responses involving interleukin 17 (IL-17) and neutrophils.
Characterisation of koalas with chlamydial illness has proven elevated expression inside all three of these main immunological pathways and monitoring of koalas’ post-vaccination has detected additional enhancements to those key pathways. These findings supply optimism {that a} chlamydial vaccine for wider distribution to koalas just isn’t far off. Recent advances in marsupial genetic data and normal nucleic acid assay expertise have moved koala immunological analysis a step nearer to different mammalian analysis techniques. However, koala-specific reagents to instantly assay cytokine ranges and cell-surface markers are nonetheless wanted to progress our understanding of koala immunology.
 Regulator of microtubule dynamics protein 3 Antibody |
|
20-abx109370 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
 Recombinant Human Regulator of Calcineurin 1 |
|
7-06082 |
CHI Scientific |
5µg |
Ask for price |
Recombinant Human Regulator of Calcineurin 1 |
|
7-06083 |
CHI Scientific |
20µg |
Ask for price |
Recombinant Human Regulator of Calcineurin 1 |
|
7-06084 |
CHI Scientific |
1mg |
Ask for price |
 Regulator of Calcineurin 2 Protein |
|
20-abx261526 |
Abbexa |
-
EUR 3418.00
-
EUR 328.00
-
EUR 230.00
|
|
|
|
 Regulator of Calcineurin 1 Protein |
|
20-abx261975 |
Abbexa |
-
EUR 4490.00
-
EUR 328.00
-
EUR 230.00
|
|
|
|
 TIMP2 Human, Tissue Inhibitor of Metalloprotease 2 Human Recombinant Protein, Sf9 |
|
PROTP16035-3 |
BosterBio |
Regular: 5ug |
EUR 317 |
|
Description: TIMP2 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 200 amino acids (27-220a.a.) and having a molecular mass of 22.5kDa. (Molecular size on SDS-PAGE will appear at approximately 18-28kDa). TIMP2 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques. |
 Recombinant Human MMP-3 Protein |
|
PROTP08254-3 |
BosterBio |
10ug |
EUR 317 |
|
Description: Matrix metalloproteinases (MMPs) are a family of endoproteases that require zinc and calcium for expressing catalytic activity. These enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. MMP-3 degrades fibronectin, laminin, collagens III, IV, and X, and cartilage proteoglycans. Recombinant human MMP-3 is a 42.8 kDa protein containing the entire catalytic N-terminal domain and the C-terminal domain (378 amino acids). |
) Recombinant Regulator Of G Protein Signaling 19 (RGS19) |
|
4-RPP367Hu01 |
Cloud-Clone |
-
EUR 503.20
-
EUR 238.00
-
EUR 1612.00
-
EUR 604.00
-
EUR 1108.00
-
EUR 400.00
-
EUR 3880.00
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Human Regulator Of G Protein Signaling 19 expressed in: E.coli |
) Recombinant Regulator Of G Protein Signaling 4 (RGS4) |
|
4-RPA978Hu01 |
Cloud-Clone |
-
EUR 530.08
-
EUR 245.00
-
EUR 1712.80
-
EUR 637.60
-
EUR 1175.20
-
EUR 418.00
-
EUR 4132.00
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Human Regulator Of G Protein Signaling 4 expressed in: E.coli |
) Recombinant Regulator Of G Protein Signaling 9 (RGS9) |
|
4-RPD699Hu01 |
Cloud-Clone |
-
EUR 431.52
-
EUR 218.00
-
EUR 1343.20
-
EUR 514.40
-
EUR 928.80
-
EUR 352.00
-
EUR 3208.00
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Human Regulator Of G Protein Signaling 9 expressed in: E.coli |
Recombinant Regulator Of G Protein Signaling 9 (RGS9) |
|
4-RPD699Mu01 |
Cloud-Clone |
-
EUR 449.44
-
EUR 223.00
-
EUR 1410.40
-
EUR 536.80
-
EUR 973.60
-
EUR 364.00
-
EUR 3376.00
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Mouse Regulator Of G Protein Signaling 9 expressed in: E.coli |
) Recombinant Regulator Of G Protein Signaling 10 (RGS10) |
|
4-RPD700Mu01 |
Cloud-Clone |
-
EUR 422.56
-
EUR 216.00
-
EUR 1309.60
-
EUR 503.20
-
EUR 906.40
-
EUR 346.00
-
EUR 3124.00
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Mouse Regulator Of G Protein Signaling 10 expressed in: E.coli |
) Recombinant Regulator Of G Protein Signaling 1 (RGS1) |
|
4-RPD701Hu01 |
Cloud-Clone |
-
EUR 458.40
-
EUR 226.00
-
EUR 1444.00
-
EUR 548.00
-
EUR 996.00
-
EUR 370.00
-
EUR 3460.00
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Human Regulator Of G Protein Signaling 1 expressed in: E.coli |
) Recombinant Regulator Of G Protein Signaling 5 (RGS5) |
|
4-RPD705Mu01 |
Cloud-Clone |
-
EUR 494.24
-
EUR 235.00
-
EUR 1578.40
-
EUR 592.80
-
EUR 1085.60
-
EUR 394.00
-
EUR 3796.00
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Mouse Regulator Of G Protein Signaling 5 expressed in: E.coli |
) Recombinant Regulator Of G Protein Signaling 6 (RGS6) |
|
4-RPD706Ra01 |
Cloud-Clone |
-
EUR 535.46
-
EUR 246.00
-
EUR 1732.96
-
EUR 644.32
-
EUR 1188.64
-
EUR 421.00
-
EUR 4182.40
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Rat Regulator Of G Protein Signaling 6 expressed in: E.coli |
) Recombinant Regulator Of G Protein Signaling 7 (RGS7) |
|
4-RPD707Hu01 |
Cloud-Clone |
-
EUR 503.20
-
EUR 238.00
-
EUR 1612.00
-
EUR 604.00
-
EUR 1108.00
-
EUR 400.00
-
EUR 3880.00
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Human Regulator Of G Protein Signaling 7 expressed in: E.coli |
 RCAN1 Regulator of Calcineurin 1 Human Recombinant Protein |
|
PROTP53805 |
BosterBio |
Regular: 20ug |
EUR 317 |
|
Description: RCAN1 Isoform-b Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 117 amino acids and having a molecular mass of 13 kDa. |
 RCAN2 Regulator of Calcineurin 2 Human Recombinant Protein |
|
PROTQ14206 |
BosterBio |
Regular: 20ug |
EUR 317 |
|
Description: RCAN2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 217 amino acids (1-197 a.a.) and having a molecular mass of 24.1kDa.;RCAN2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
 Recombinant Human Regulator of G-Protein Signaling 2 |
|
7-06115 |
CHI Scientific |
1µg |
Ask for price |
Recombinant Human Regulator of G-Protein Signaling 2 |
|
7-06116 |
CHI Scientific |
5µg |
Ask for price |
Recombinant Human Regulator of G-Protein Signaling 2 |
|
7-06117 |
CHI Scientific |
50µg |
Ask for price |
 Recombinant Human Regulator of G-Protein Signaling 5 |
|
7-06118 |
CHI Scientific |
5µg |
Ask for price |
Recombinant Human Regulator of G-Protein Signaling 5 |
|
7-06119 |
CHI Scientific |
25µg |
Ask for price |
Recombinant Human Regulator of G-Protein Signaling 5 |
|
7-06120 |
CHI Scientific |
1mg |
Ask for price |
 Recombinant Human Regulator of G-Protein Signaling 4 |
|
7-06121 |
CHI Scientific |
2µg |
Ask for price |
Recombinant Human Regulator of G-Protein Signaling 4 |
|
7-06122 |
CHI Scientific |
10µg |
Ask for price |
Recombinant Human Regulator of G-Protein Signaling 4 |
|
7-06123 |
CHI Scientific |
1mg |
Ask for price |
 Recombinant Human Regulator of G-Protein Signaling 10 |
|
7-06124 |
CHI Scientific |
5µg |
Ask for price |
Recombinant Human Regulator of G-Protein Signaling 10 |
|
7-06125 |
CHI Scientific |
25µg |
Ask for price |
Recombinant Human Regulator of G-Protein Signaling 10 |
|
7-06126 |
CHI Scientific |
1mg |
Ask for price |
 Recombinant Human Regulator of G-Protein Signaling 16 |
|
7-06127 |
CHI Scientific |
2µg |
Ask for price |
Recombinant Human Regulator of G-Protein Signaling 16 |
|
7-06128 |
CHI Scientific |
10µg |
Ask for price |
Recombinant Human Regulator of G-Protein Signaling 16 |
|
7-06129 |
CHI Scientific |
1mg |
Ask for price |
 Recombinant Human Regulator of G-Protein Signaling 19 |
|
7-06130 |
CHI Scientific |
5µg |
Ask for price |
Recombinant Human Regulator of G-Protein Signaling 19 |
|
7-06131 |
CHI Scientific |
20µg |
Ask for price |
Recombinant Human Regulator of G-Protein Signaling 19 |
|
7-06132 |
CHI Scientific |
1mg |
Ask for price |
 Recombinant Human Regulator of G-Protein Signaling 21 |
|
7-06133 |
CHI Scientific |
5µg |
Ask for price |
Recombinant Human Regulator of G-Protein Signaling 21 |
|
7-06134 |
CHI Scientific |
20µg |
Ask for price |
Recombinant Human Regulator of G-Protein Signaling 21 |
|
7-06135 |
CHI Scientific |
1mg |
Ask for price |
 Recombinant mouse Isoform 3 of Transcription elongation regulator 1 |
|
P2600 |
FN Test |
100ug |
Ask for price |
|
|
|
Description: Recombinant protein for mouse Isoform 3 of Transcription elongation regulator 1 |
) Human Regulator of microtubule dynamics protein 3 (RMDN3) |
|
1-CSB-EP836307HU |
Cusabio |
-
EUR 380.00
-
EUR 214.00
-
EUR 1309.00
-
EUR 560.00
-
EUR 873.00
-
EUR 262.00
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
|
|
Description: Recombinant Human Regulator of microtubule dynamics protein 3(RMDN3) expressed in E.coli |
) Regulator of microtubule dynamics protein 3 Antibody (FITC) |
|
20-abx107291 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
 Antibody) Regulator of G Protein Signaling 3 (RGS3) Antibody |
|
20-abx130745 |
Abbexa |
-
EUR 439.00
-
EUR 133.00
-
EUR 1233.00
-
EUR 592.00
-
EUR 328.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
 Antibody) Regulator of G-Protein Signaling 3 (RGS3) Antibody |
|
20-abx115113 |
Abbexa |
|
|
|
|
) Regulator of microtubule dynamics protein 3 Antibody (HRP) |
|
20-abx108711 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
Regulator of G-Protein Signaling 3 (RGS3) Antibody |
|
20-abx321746 |
Abbexa |
|
|
|
|
Regulator of G-Protein Signaling 3 (RGS3) Antibody |
|
abx145161-100ug |
Abbexa |
100 ug |
EUR 391 |
|
|
Regulator of G-Protein Signaling 3 (RGS3) Antibody |
|
20-abx006835 |
Abbexa |
-
EUR 411.00
-
EUR 592.00
-
EUR 182.00
-
EUR 314.00
|
- 100 ul
- 200 ul
- 20 ul
- 50 ul
|
|
|
Regulator of G-Protein Signaling 3 (RGS3) Antibody |
|
abx237270-100ug |
Abbexa |
100 ug |
EUR 509 |
|
|
 DiscoveryPak? Stem Cell Fate Regulator Set I |
|
K852-3 |
Biovision |
|
EUR 566 |
 DiscoveryPak? Stem Cell Fate Regulator Set III |
|
K854-3 |
Biovision |
|
EUR 425 |
 DiscoveryPak? Stem Cell Fate Regulator Set IV |
|
K855-3 |
Biovision |
|
EUR 457 |
 Protein) Mouse Regulator Of G Protein Signaling 3 (RGS3) Protein |
|
20-abx650448 |
Abbexa |
-
EUR 718.00
-
EUR 286.00
-
EUR 2221.00
-
EUR 857.00
-
EUR 509.00
|
- 100 ug
- 10 ug
- 1 mg
- 200 ug
- 50 ug
|
|
|
 Recombinant Human Down-Regulator of Transcription 1 |
|
7-04996 |
CHI Scientific |
5µg |
Ask for price |
Recombinant Human Down-Regulator of Transcription 1 |
|
7-04997 |
CHI Scientific |
25µg |
Ask for price |
Recombinant Human Down-Regulator of Transcription 1 |
|
7-04998 |
CHI Scientific |
1mg |
Ask for price |
 Recombinant human Regulator of nonsense transcripts 3B |
|
P2525 |
FN Test |
100ug |
Ask for price |
|
|
|
Description: Recombinant protein for human Regulator of nonsense transcripts 3B |
 IL-3 Interleukin-3 Human Recombinant Protein, His Tag |
|
PROTP08700-3 |
BosterBio |
Regular: 50ug |
EUR 317 |
|
Description: Interleukin-3 Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 154 amino acids fragment (20-152) and having a total molecular mass of 17.3kDa and fused with a 20 aa N-terminal His tag. ;The IL3 His is purified by proprietary chromatographic techniques. |
 Antibody) Regulator of Microtubule Dynamics 3 (RMDN3) Antibody |
|
20-abx322244 |
Abbexa |
|
|
|
|
Regulator of Microtubule Dynamics 3 (RMDN3) Antibody |
|
20-abx141496 |
Abbexa |
-
EUR 370.00
-
EUR 606.00
-
EUR 300.00
|
|
|
|
 Antibody) Regulator Of Microtubule Dynamics 3 (RMDN3) Antibody |
|
20-abx213796 |
Abbexa |
|
|
|
|
Regulator Of Microtubule Dynamics 3 (RMDN3) Antibody |
|
20-abx214055 |
Abbexa |
|
|
|
|
 DR1 Down-Regulator of Transcription 1 Human Recombinant Protein |
|
PROTQ01658 |
BosterBio |
Regular: 25ug |
EUR 317 |
|
Description: DR1 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 196 amino acids (1-176 a.a.) and having a molecular mass of 21.6 kDa. The DR1 is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. |
 RGS2 Regulator of G-Protein Signaling 2 Human Recombinant Protein |
|
PROTP41220 |
BosterBio |
Regular: 5ug |
EUR 317 |
|
Description: RGS2 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 231 amino acids (1-211a.a.) and having a molecular mass of 26.5 kDa. ;RGS2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
 RGS19 Regulator of G-Protein Signaling 19 Human Recombinant Protein |
|
PROTP49795 |
BosterBio |
Regular: 20ug |
EUR 317 |
|
Description: RGS19 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 327 amino acids (1-217a.a.) and having a molecular mass of 26.7kDa.;RGS19 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
 RGS4 Regulator of G-Protein Signaling 4 Human Recombinant Protein |
|
PROTP49798 |
BosterBio |
Regular: 10ug |
EUR 317 |
|
Description: RGS4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 225 amino acids (1-205 a.a.) and having a molecular mass of 25.4kDa.;RGS4 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
 RGS1 Regulator of G-Protein Signaling 1 Human Recombinant Protein |
|
PROTQ08116 |
BosterBio |
Regular: 20ug |
EUR 317 |
|
Description: RGS1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 233 amino acids (1-209 a.a) and having a molecular mass of 26kDa.;RGS1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
 RGS21 Regulator of G-Protein Signaling 21 Human Recombinant Protein |
|
PROTQ2M5E4 |
BosterBio |
Regular: 20ug |
EUR 317 |
|
Description: RGS21 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 176 amino acids (1-152 a.a.) and having a molecular mass of 20.2kDa.;RGS21 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
 RGS17 Regulator of G-Protein Signaling 17 Human Recombinant Protein |
|
PROTQ9UGC6 |
BosterBio |
Regular: 25ug |
EUR 317 |
|
Description: RGS17 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 230 amino acids (1-210) and having a molecular mass of 26.5 kDa.;The RGS17 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. |
 RGS16 Regulator of G-Protein Signaling 16 Human Recombinant Protein |
|
PROTO15492 |
BosterBio |
Regular: 10ug |
EUR 317 |
|
Description: RGS16 Human Recombinant fused to 20 amino acid His Tag at N-terminal produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 222 amino acids (1-202 a.a.) and having a molecular mass of 24.9 kDa. _x000D_ The RGS16 is purified by proprietary chromatographic techniques._x000D_ |
 RGS5 Regulator of G-Protein Signaling 5 Human Recombinant Protein |
|
PROTO15539 |
BosterBio |
Regular: 25ug |
EUR 317 |
|
Description: RGS5 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 205 amino acids (1-181 a.a.) and having a molecular mass of 23.5kDa.;RGS5 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
 RGS14 Regulator of G-Protein Signaling 14 Human Recombinant Protein |
|
PROTO43566 |
BosterBio |
Regular: 10ug |
EUR 317 |
|
Description: RGS14 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 586 amino acids (1-566 a.a) and having a molecular mass of 63.6kDa.;RGS14 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
 RGS10 Regulator of G-Protein Signaling 10 Human Recombinant Protein |
|
PROTO43665 |
BosterBio |
Regular: 25ug |
EUR 317 |
|
Description: RGS10 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 205 amino acids (1-181) and having a molecular mass of 23.7 kDa.;The RGS10 is fused to a 24 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. |
 Regulator of G-Protein Signaling 19 Protein |
|
20-abx260826 |
Abbexa |
-
EUR 3418.00
-
EUR 328.00
-
EUR 230.00
|
|
|
|
 Regulator of G-Protein Signaling 10 Protein |
|
20-abx261468 |
Abbexa |
-
EUR 3418.00
-
EUR 328.00
-
EUR 230.00
|
|
|
|
 Regulator of G-Protein Signaling 21 Protein |
|
20-abx261473 |
Abbexa |
-
EUR 3418.00
-
EUR 328.00
-
EUR 230.00
|
|
|
|
 Regulator of G-Protein Signaling 17 Protein |
|
20-abx261493 |
Abbexa |
-
EUR 3418.00
-
EUR 328.00
-
EUR 230.00
|
|
|
|
 Regulator of G-Protein Signaling 16 Protein |
|
20-abx262881 |
Abbexa |
-
EUR 328.00
-
EUR 6397.00
-
EUR 230.00
|
|
|
|
 Regulator of G-Protein Signaling 14 Protein |
|
20-abx263291 |
Abbexa |
-
EUR 1609.00
-
EUR 328.00
-
EUR 230.00
|
|
|
|
 Human Adaptive & Innate Immune Response Primer Library |
|
HAIIR-I |
Real Time Primers |
1 set |
EUR 548 |
 Recombinant human Negative regulator of reactive oxygen species |
|
P1956 |
FN Test |
100ug |
Ask for price |
|
|
|
Description: Recombinant protein for human Negative regulator of reactive oxygen species |
 TGF-b-3 Transforming Growth Factor-Beta 3 Human Recombinant Protein, Plant |
|
PROTP10600-3 |
BosterBio |
Regular: 5ug |
EUR 317 |
|
Description: TGFB3 Human Recombinant produced in plant is a disulfide-linked homodimeric, glycosylated, polypeptide chain containing 118 amino acids and having a molecular mass of 27.2kDa. ;The TGFB3 is fused to 6xHis tag at N-terminus and purified by standard chromatographic techniques. |
 Regulator Of Calcineurin 2 Antibody |
|
20-abx115103 |
Abbexa |
|
|
|
|
 Active regulator of SIRT1 Antibody |
|
20-abx109494 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
 Recombinant Human Active regulator of SIRT1 Protein, GST, E.coli-100ug |
|
QP8330-ec-100ug |
EnQuireBio |
100ug |
EUR 408 |
 Recombinant Human Active regulator of SIRT1 Protein, GST, E.coli-10ug |
|
QP8330-ec-10ug |
EnQuireBio |
10ug |
EUR 200 |
 Recombinant Human Active regulator of SIRT1 Protein, GST, E.coli-1mg |
|
QP8330-ec-1mg |
EnQuireBio |
1mg |
EUR 1632 |
 Recombinant Human Active regulator of SIRT1 Protein, GST, E.coli-200ug |
|
QP8330-ec-200ug |
EnQuireBio |
200ug |
EUR 634 |
 Recombinant Human Active regulator of SIRT1 Protein, GST, E.coli-500ug |
|
QP8330-ec-500ug |
EnQuireBio |
500ug |
EUR 1060 |
 Recombinant Human Active regulator of SIRT1 Protein, GST, E.coli-50ug |
|
QP8330-ec-50ug |
EnQuireBio |
50ug |
EUR 263 |
) Human Active regulator of SIRT1 protein (RPS19BP1) |
|
1-CSB-RP006544h |
Cusabio |
-
EUR 380.00
-
EUR 214.00
-
EUR 1309.00
-
EUR 560.00
-
EUR 873.00
-
EUR 262.00
|
- 100ug
- 10ug
- 1MG
- 200ug
- 500ug
- 50ug
|
|
|
|
Description: Recombinant Human Active regulator of SIRT1 protein(RPS19BP1) expressed in E.coli |
 Antibody) Protein Regulator of Cytokinesis 1 (PRC1) Antibody |
|
20-abx114861 |
Abbexa |
|
|
|
|
 Regulator Of G-Protein Signaling 7 Antibody |
|
20-abx115116 |
Abbexa |
|
|
|
|
 Regulator Of G-Protein Signaling 9 Antibody |
|
20-abx115117 |
Abbexa |
|
|
|
|
 Regulator of G-protein signaling 20 Antibody |
|
20-abx109369 |
Abbexa |
-
EUR 411.00
-
EUR 1845.00
-
EUR 599.00
-
EUR 182.00
-
EUR 300.00
|
- 100 ug
- 1 mg
- 200 ug
- 20 ug
- 50 ug
|
|
|
Protein Regulator of Cytokinesis 1 (PRC1) Antibody |
|
abx036162-100ug |
Abbexa |
100 ug |
EUR 391 |
|
|
Protein Regulator of Cytokinesis 1 (PRC1) Antibody |
|
20-abx142167 |
Abbexa |
-
EUR 370.00
-
EUR 606.00
-
EUR 314.00
|
|
|
|
Protein Regulator of Cytokinesis 1 (PRC1) Antibody |
|
20-abx006417 |
Abbexa |
-
EUR 411.00
-
EUR 592.00
-
EUR 182.00
-
EUR 314.00
|
- 100 ul
- 200 ul
- 20 ul
- 50 ul
|
|
|
Protein Regulator of Cytokinesis 1 (PRC1) Antibody |
|
abx236748-100ug |
Abbexa |
100 ug |
EUR 481 |
|
|
Protein Regulator of Cytokinesis 1 (PRC1) Antibody |
|
abx236749-100ug |
Abbexa |
100 ug |
EUR 551 |
|
|
 Antibody) Protein regulator of cytokinesis 1 (PRC1) Antibody |
|
20-abx212926 |
Abbexa |
|
|
|
|
Protein regulator of cytokinesis 1 (PRC1) Antibody |
|
20-abx325006 |
Abbexa |
|
|
|
|
 Polyclonal Antibody (Mouse)) Regulator Of G Protein Signaling 3 (RGS3) Polyclonal Antibody (Mouse) |
|
4-PAD703Mu01 |
Cloud-Clone |
-
EUR 251.00
-
EUR 2576.00
-
EUR 640.00
-
EUR 316.00
-
EUR 215.00
|
- 100ul
- 10ml
- 1ml
- 200ul
- 20ul
|
|
|
|
Description: A Rabbit polyclonal antibody against Mouse Regulator Of G Protein Signaling 3 (RGS3) |
 Human RGS3/ Regulator of G-protein signaling 3 ELISA Kit |
|
E2148Hu |
Sunlong |
1 Kit |
EUR 571 |
 Mouse Rgs3/ Regulator of G-protein signaling 3 ELISA Kit |
|
E1268Mo |
Sunlong |
1 Kit |
EUR 571 |
 ELISA Kit) Rat Regulator of G-protein signaling 3 (RGS3) ELISA Kit |
|
abx512364-96tests |
Abbexa |
96 tests |
EUR 668 |
|
|
 ELISA Kit) Human Regulator of G-protein signaling 3 (RGS3) ELISA Kit |
|
abx253760-96tests |
Abbexa |
96 tests |
EUR 668 |
|
|
 ELISA Kit) Mouse Regulator of G-protein signaling 3 (RGS3) ELISA Kit |
|
abx254715-96tests |
Abbexa |
96 tests |
EUR 668 |
|
|
 ELISA kit for Mouse Regulator of G-protein signaling 3 |
|
EK1551 |
SAB |
96 tests |
EUR 553 |
|
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse Regulator of G-protein signaling 3 in samples from serum, plasma, tissue homogenates and other biological fluids. |
 ELISA Kit) Mouse Rgs3(Regulator of G-protein signaling 3) ELISA Kit |
|
EM0359 |
FN Test |
96T |
EUR 567.6 |
|
|
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml |
 ELISA Kit) Human RGS3(Regulator of G-protein signaling 3) ELISA Kit |
|
EH0802 |
FN Test |
96T |
EUR 567.6 |
|
|
|
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml |
 Human Regulator of G-protein signaling 3, RGS3 ELISA Kit |
|
ELA-E10251h |
Lifescience Market |
96 Tests |
EUR 824 |
 Mouse Regulator of G-protein signaling 3, RGS3 ELISA Kit |
|
ELA-E10251m |
Lifescience Market |
96 Tests |
EUR 865 |
 Rat Regulator of G-protein signaling 3, RGS3 ELISA Kit |
|
ELA-E10251r |
Lifescience Market |
96 Tests |
EUR 886 |
 PLGF3 Human, Placenta Growth Factor-3 Human Recombinant Protein, sf9 |
|
PROTP49763-3 |
BosterBio |
Regular: 25ug |
EUR 317 |
|
Description: PLGF3 Human Recombinant produced in Spodoptera frugiperda is a glycosylated homodimer containing 2 chains of 203 amino acids (Leu19-Arg221) and having a molecular mass of 58kDa.;The PLGF-3 is purified by proprietary chromatographic techniques. |
 Protein) Regulator Of G Protein Signaling 5 (RGS5) Protein |
|
20-abx261477 |
Abbexa |
-
EUR 3418.00
-
EUR 328.00
-
EUR 230.00
|
|
|
|
 Protein) Regulator Of G Protein Signaling 1 (RGS1) Protein |
|
20-abx261913 |
Abbexa |
-
EUR 4490.00
-
EUR 328.00
-
EUR 230.00
|
|
|
|
 Protein) Regulator Of G Protein Signaling 4 (RGS4) Protein |
|
20-abx262913 |
Abbexa |
-
EUR 328.00
-
EUR 6397.00
-
EUR 230.00
|
|
|
|
 Protein) Regulator Of G Protein Signaling 2 (RGS2) Protein |
|
20-abx263401 |
Abbexa |
-
EUR 230.00
-
EUR 1609.00
-
EUR 328.00
|
|
|
|
 IRGM Immunity-Related GTPase Family, M Human Recombinant Protein |
|
PROTA1A4Y4 |
BosterBio |
Regular: 20ug |
EUR 317 |
|
Description: IRGM Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 180 amino acids (23-181) and having a molecular mass of 20.1 kDa. IRGM is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. |
) Recombinant IK Cytokine, Down Regulator Of HLA II (IK) |
|
4-RPP940Hu01 |
Cloud-Clone |
-
EUR 501.41
-
EUR 237.00
-
EUR 1605.28
-
EUR 601.76
-
EUR 1103.52
-
EUR 398.00
-
EUR 3863.20
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Human IK Cytokine, Down Regulator Of HLA II expressed in: E.coli |
) Recombinant Down Regulator Of Transcription 1, TBP Binding (DR1) |
|
4-RPB259Hu01 |
Cloud-Clone |
-
EUR 485.28
-
EUR 233.00
-
EUR 1544.80
-
EUR 581.60
-
EUR 1063.20
-
EUR 388.00
-
EUR 3712.00
|
- 100 ug
- 10ug
- 1 mg
- 200 ug
- 500 ug
- 50ug
- 5 mg
|
|
|
|
Description: Recombinant Human Down Regulator Of Transcription 1, TBP Binding expressed in: E.coli |
Human Angiopoietin-like Protein 3 (17-460 a.a.) Human Recombinant Protein) ANGPTL3 (17-460)Human Angiopoietin-like Protein 3 (17-460 a.a.) Human Recombinant Protein |
|
PROTQ9Y5C1-3 |
BosterBio |
Regular: 10ug |
EUR 317 |
|
Description: ANGPTL3 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 453 amino acids (17-460 a.a.) and having a molecular mass of 52.9kDa (Migrates at 25-70kDa on SDS-PAGE under reducing conditions). |
 Recombinant Human Regulator of microtubule dynamics protein 1, His, E.coli-100ug |
|
QP7878-ec-100ug |
EnQuireBio |
100ug |
EUR 408 |
 Recombinant Human Regulator of microtubule dynamics protein 1, His, E.coli-10ug |
|
QP7878-ec-10ug |
EnQuireBio |
10ug |
EUR 200 |
 Recombinant Human Regulator of microtubule dynamics protein 1, His, E.coli-1mg |
|
QP7878-ec-1mg |
EnQuireBio |
1mg |
EUR 1632 |
 Recombinant Human Regulator of microtubule dynamics protein 1, His, E.coli-200ug |
|
QP7878-ec-200ug |
EnQuireBio |
200ug |
EUR 634 |
 Recombinant Human Regulator of microtubule dynamics protein 1, His, E.coli-500ug |
|
QP7878-ec-500ug |
EnQuireBio |
500ug |
EUR 1060 |
 Recombinant Human Regulator of microtubule dynamics protein 1, His, E.coli-50ug |
|
QP7878-ec-50ug |
EnQuireBio |
50ug |
EUR 263 |
 Recombinant Human Regulator of G-protein signaling 10 Protein, GST, E.coli-100ug |
|
QP6602-ec-100ug |
EnQuireBio |
100ug |
EUR 408 |
 Recombinant Human Regulator of G-protein signaling 10 Protein, GST, E.coli-10ug |
|
QP6602-ec-10ug |
EnQuireBio |
10ug |
EUR 200 |
 Recombinant Human Regulator of G-protein signaling 10 Protein, GST, E.coli-1mg |
|
QP6602-ec-1mg |
EnQuireBio |
1mg |
EUR 1632 |
 Recombinant Human Regulator of G-protein signaling 10 Protein, GST, E.coli-200ug |
|
QP6602-ec-200ug |
EnQuireBio |
200ug |
EUR 634 |
 Recombinant Human Regulator of G-protein signaling 10 Protein, GST, E.coli-500ug |
|
QP6602-ec-500ug |
EnQuireBio |
500ug |
EUR 1060 |
 Recombinant Human Regulator of G-protein signaling 10 Protein, GST, E.coli-50ug |
|
QP6602-ec-50ug |
EnQuireBio |
50ug |
EUR 263 |
 Recombinant Human Regulator of G-protein signaling 20 Protein, GST, E.coli-100ug |
|
QP6604-ec-100ug |
EnQuireBio |
100ug |
EUR 408 |
 Recombinant Human Regulator of G-protein signaling 20 Protein, GST, E.coli-10ug |
|
QP6604-ec-10ug |
EnQuireBio |
10ug |
EUR 200 |
 Recombinant Human Regulator of G-protein signaling 20 Protein, GST, E.coli-1mg |
|
QP6604-ec-1mg |
EnQuireBio |
1mg |
EUR 1632 |
 Recombinant Human Regulator of G-protein signaling 20 Protein, GST, E.coli-200ug |
|
QP6604-ec-200ug |
EnQuireBio |
200ug |
EUR 634 |
 Recombinant Human Regulator of G-protein signaling 20 Protein, GST, E.coli-500ug |
|
QP6604-ec-500ug |
EnQuireBio |
500ug |
EUR 1060 |
 Recombinant Human Regulator of G-protein signaling 20 Protein, GST, E.coli-50ug |
|
QP6604-ec-50ug |
EnQuireBio |
50ug |
EUR 263 |
 Recombinant Human Regulator of G-protein signaling 7 Protein, His, E.coli-100ug |
|
QP6606-ec-100ug |
EnQuireBio |
100ug |
EUR 408 |
 Recombinant Human Regulator of G-protein signaling 7 Protein, His, E.coli-10ug |
|
QP6606-ec-10ug |
EnQuireBio |
10ug |
EUR 200 |
 Recombinant Human Regulator of G-protein signaling 7 Protein, His, E.coli-1mg |
|
QP6606-ec-1mg |
EnQuireBio |
1mg |
EUR 1632 |
 Recombinant Human Regulator of G-protein signaling 7 Protein, His, E.coli-200ug |
|
QP6606-ec-200ug |
EnQuireBio |
200ug |
EUR 634 |
 Recombinant Human Regulator of G-protein signaling 7 Protein, His, E.coli-500ug |
|
QP6606-ec-500ug |
EnQuireBio |
500ug |
EUR 1060 |
 Recombinant Human Regulator of G-protein signaling 7 Protein, His, E.coli-50ug |
|
QP6606-ec-50ug |
EnQuireBio |
50ug |
EUR 263 |
 Recombinant Human TPO Protein |
|
PROTP40225-3 |
BosterBio |
10ug |
EUR 317 |
|
Description: TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and murine TPO exhibits cross-species reactivity. Recombinant human TPO is a fully biologically active 174 amino acid polypeptide (18.6 kDa), which contains the erythropoietin-like domain of the full length TPO protein. |
 Recombinant Human Leptin Protein |
|
PROTP41159-3 |
BosterBio |
1mg |
EUR 317 |
|
Description: Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models. Recombinant human Leptin is a 16.0 kDa protein containing 147 amino acid residues. |
 Recombinant Human Sox2 Protein |
|
PROTP48431-3 |
BosterBio |
25ug |
EUR 317 |
|
Description: Sox2, also known as sex determining region Y (SRY)-box 2, belongs to a diverse family of structurally-related transcription factors whose primary structure contains a 79-residue DNA-binding domain, called high mobility group (HMG) box. It plays an essential role in maintaining the pluripotency of embryonic stem cells (ESC) and determination of cell fate. Microarray analysis showed that Sox2 regulates the expression of multiple genes involved in embryonic development including FGF-4, YES1 and ZFP206. Sox2 acts as a transcriptional activator after forming a ternary complex with Oct3/4 and a conserved non-coding DNA sequence (CNS1) located approximately 2 kb upstream of the RAX promoter. The introduction of Sox2, Oct4, Myc, and Klf4, into human dermal fibroblasts isolated from a skin biopsy of a healthy research fellow was sufficient to confer a pluripotent state upon the fibroblast genome. The reprogrammed cells thus obtained resemble ESC in morphology, gene expression, and in the capacity to form teratomas in immune-deficient mice. Recombinant human Sox2 is a 34.3 kDa protein containing 317 amino-acid residues. |
 Recombinant Human NOGGIN Protein |
|
PROTQ13253-3 |
BosterBio |
20ug |
EUR 317 |
|
Description: Noggin belongs to a group of diffusible proteins which bind to ligands of the TGF-β family and regulate their activity by inhibiting their access to signaling receptors. The interplay between TGF-β ligands and their natural antagonists has major biological significance during development processes, in which cellular response can vary considerably depending upon the local concentration of the signaling molecule. Noggin was originally identified as a BMP-4 antagonist whose action is critical for proper formation of the head and other dorsal structures. Consequently, Noggin has been shown to modulate the activities of other BMPs including BMP-2,-7,-13, and -14. Targeted deletion of Noggin in mice results in prenatal death and recessive phenotype displaying a severely malformed skeletal system. Conversely, transgenic mice over-expressing Noggin in mature osteoblasts display impaired osteoblastic differentiation, reduced bone formation, and severe osteoporosis. Recombinant human Noggin is a 46 kDa disulfide-linked homodimer (120-10C) consisting of two 206 amino acid polypeptide chains. Monomeric glycosylated Noggin migrates at an apparent molecular weight of approximately 28.0-33.0 kDa by SDS PAGE analysis under reducing conditions. |
 Recombinant Human Epigen Protein |
|
PROTQ6UW88-3 |
BosterBio |
25ug |
EUR 317 |
|
Description: Epigen is an EGF-related polypeptide growth factor that signals through the ErbB receptor-1. It is produced in several tissues, including the testis, liver, heart and in certain tumor cells. Epigen is mitogenic for fibroblasts and epithelial cells. Human Epigen is initially synthesized as a glycosylated 14.7 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce a mature soluble sequence. Recombinant human Epigen is a 7.9kDa monomeric protein, containing 72 amino acid residues, which comprises the EGF homologous portion of the Epigen precursor. |
 Recombinant Human Chemerin Protein |
|
PROTQ99969-3 |
BosterBio |
25ug |
EUR 317 |
|
Description: Chemerin is a secreted chemoattractant protein that can signal through the chemokine like receptor-1 (CMKLR1). It is expressed in various tissues, including white adipose tissue, and circulates in blood as an inactive 143 amino acid precursor protein. Biologically active Chemerin is generated by proteolytic removal of C-terminal residues by several circulating proteases. Chemerin acts as a chemoattractant for cells expressing the CMKLR1 receptor, which includes certain dendritic cells, macrophages, and adipocytes. Recombinant human Chemerin is a 15.6 kDa protein consisting of 135 amino acid residues. |
Prostate carcinoma (PC) is the second commonest most cancers in males. When the illness turns into unresponsive to androgen deprivation remedy, the remaining therapy choices are of restricted profit. Despite intense efforts, none of the T cell-based immunotherapeutic methods that in the meantime have turn into a cornerstone for therapy of different malignancies is established in PC. This refers to immune checkpoint inhibition (CI), which usually reinforces T cell immunity in addition to chimeric antigen receptor T (CAR-T) cells and bispecific antibodies (bsAbs) that stimulate the T cell receptor/CD3-complex and mobilize T cells in a focused method.
In normal, in comparison with CAR-T cells, bsAb would have the benefit of being an “off the shelf” reagent related to much less preparative effort, however at current, regardless of monumental efforts, neither CAR-T cells nor bsAbs are profitable in stable tumors. Here, we give attention to the varied bispecific constructs which are presently in growth for therapy of PC, and talk about underlying ideas and the state of medical analysis in addition to future views.
